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Jeanne Marie Berner

Researcher at University of Oslo

Publications -  17
Citations -  1116

Jeanne Marie Berner is an academic researcher from University of Oslo. The author has contributed to research in topics: Sarcoma & Fluorescence in situ hybridization. The author has an hindex of 14, co-authored 17 publications receiving 1091 citations. Previous affiliations of Jeanne Marie Berner include Rikshospitalet–Radiumhospitalet & Oslo University Hospital.

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Structure of the Supernumerary Ring and Giant Rod Chromosomes in Adipose Tissue Tumors

TL;DR: This work extensively investigated the structure and composition of rings and giant rods in a series of 17 WDLPS‐ALP samples and three intra‐ or intermuscular lipomas (IMLP), revealing a unique combination of particular features strikingly related to these tumors.
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Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas

TL;DR: The data suggest that amplification of at least three different regions within the 12q13–15 segment may be selected for in tumor cells involving MDM2, CDK4, or a more distally located gene, possibly near D12S8.
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Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1.

TL;DR: The data indicate that aberrations of these functionally related genes, or in regulation of the expression of the kinase, the activator or the inhibitor, may participate in sarcoma development and suggest that homozygous CDKN2 deletions may be of dissimilar significance in different sarcomA subtypes.
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HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas

TL;DR: It is striking that the gene was frequently amplified or rearranged in well differentiated liposarcomas, the malignant counterpart of lipomas, and it seems conceivable that high levels of either full length or truncated hmgic could be relevant for the etiology of these tumors.