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Anne M. Kong
Researcher at St. Vincent's Institute of Medical Research
Publications - 11
Citations - 333
Anne M. Kong is an academic researcher from St. Vincent's Institute of Medical Research. The author has contributed to research in topics: Induced pluripotent stem cell & Tissue engineering. The author has an hindex of 6, co-authored 8 publications receiving 254 citations.
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Journal ArticleDOI
Three Dimensional Collagen Scaffold Promotes Intrinsic Vascularisation for Tissue Engineering Applications
Elsa C. Chan,Shyh Ming Kuo,Anne M. Kong,Wayne A. Morrison,Wayne A. Morrison,Wayne A. Morrison,Gregory J. Dusting,Gregory J. Dusting,Geraldine M. Mitchell,Geraldine M. Mitchell,Geraldine M. Mitchell,Shiang Y. Lim,Shiang Y. Lim,Guei-Sheung Liu +13 more
TL;DR: These collagen scaffolds are biocompatible and could be used to grow more robust vascularized tissue engineering grafts with improved the survival of implanted cells.
Journal ArticleDOI
Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells.
Ashfaqul Hoque,Priyadharshini Sivakumaran,Simon T. Bond,Naomi X.Y. Ling,Anne M. Kong,John W. Scott,Nadeeka Bandara,Nadeeka Bandara,Damián Hernández,Guei-Sheung Liu,Guei-Sheung Liu,Raymond C.B. Wong,Michael T. Ryan,Derek J. Hausenloy,Bruce E. Kemp,Bruce E. Kemp,Jonathan S. Oakhill,Jonathan S. Oakhill,Brian G. Drew,Alice Pébay,Shiang Y. Lim,Shiang Y. Lim +21 more
TL;DR: It is demonstrated that changes in mitochondrial morphology from a small granular fragmented phenotype in pluripotent stem cells to a filamentous reticular elongated network in differentiated cardiomyocytes are required for cardiac mesodermal differentiation and suggested that Drp1 may represent a new molecular target for future development of strategies to promote the differentiation of human iPSCs into cardiac lineages for patient-specific cardiac regenerative medicine.
Journal ArticleDOI
Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction.
Andrew R Kompa,Andrew R Kompa,David W. Greening,David W. Greening,Anne M. Kong,Paul J. McMillan,Haoyun Fang,Ritika Saxena,Ritika Saxena,Raymond C.B. Wong,Raymond C.B. Wong,Jarmon G Lees,Jarmon G Lees,Priyadharshini Sivakumaran,Andrew Newcomb,Bakhos A. Tannous,Cameron Kos,Lina Mariana,Thomas Loudovaris,Derek J. Hausenloy,Shiang Y. Lim,Shiang Y. Lim +21 more
TL;DR: Sustained delivery of the secretome from cardiac stem cells using an immune-isolation device, implanted subcutaneously, to produce cardioreparative effects following myocardial infarction is demonstrated.
Journal ArticleDOI
Characterization of isolated liver sinusoidal endothelial cells for liver bioengineering
Aaron M. Dingle,Aaron M. Dingle,Kiryu K. Yap,Kiryu K. Yap,Yi-Wen Gerrand,Yi-Wen Gerrand,Carolyn Taylor,Carolyn Taylor,Carolyn Taylor,E. Keramidaris,Zerina Lokmic,Zerina Lokmic,Anne M. Kong,Heidi Peters,Heidi Peters,Wayne A. Morrison,Wayne A. Morrison,Wayne A. Morrison,Geraldine M. Mitchell,Geraldine M. Mitchell,Geraldine M. Mitchell +20 more
TL;DR: Isolated mouse LSECs express a panel of vascular-related cell markers and demonstrate substantial vascular capillary-forming ability in vitro and in vivo, reinforcing their pro-regenerative capabilities for liver tissue engineering studies.
Journal ArticleDOI
Bio-engineering a tissue flap utilizing a porous scaffold incorporating a human induced pluripotent stem cell-derived endothelial cell capillary network connected to a vascular pedicle.
Anne M. Kong,Kiryu K. Yap,Shiang Y. Lim,Diego Marre,Alice Pébay,Yi-Wen Gerrand,Jarmon G Lees,Jason A. Palmer,Wayne A. Morrison,Geraldine M. Mitchell,Geraldine M. Mitchell +10 more
TL;DR: It is feasible to form an autologous tissue flap derived from a hiPSC EC capillary network assembled in vitro, and functionally connect to a vascular pedicle in vivo that could be utilized in complex wound repair for chronic or acute wounds.