G
Guei-Sheung Liu
Researcher at Menzies Research Institute
Publications - 105
Citations - 2691
Guei-Sheung Liu is an academic researcher from Menzies Research Institute. The author has contributed to research in topics: NADPH oxidase & Angiogenesis. The author has an hindex of 24, co-authored 92 publications receiving 2051 citations. Previous affiliations of Guei-Sheung Liu include Jinan University & University of Tasmania.
Papers
More filters
Journal ArticleDOI
NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses
TL;DR: It is proposed that pharmacological inhibition of the Nox4 function may represent a novel approach in treatment of fibrotic disorders and accumulating evidence suggests that Nox 4 NADPH oxidase may be an important downstream effector in mediating TGF-β-induced fibrosis.
Journal ArticleDOI
Differentiation of Human Adipose-Derived Stem Cells into Fat Involves Reactive Oxygen Species and Forkhead Box O1 Mediated Upregulation of Antioxidant Enzymes
Masayoshi Higuchi,Gregory J. Dusting,Hitesh M Peshavariya,Fan Jiang,Sarah Tzu-Feng Hsiao,Elsa C. Chan,Guei-Sheung Liu +6 more
TL;DR: It is suggested that ROS promoted lipid accumulation in hASC undergoing adipogenesis, and antioxidant enzymes upregulated by IDII during adipogenesis were blunted by FOXO1 silencing, which suppressed significantly IDII-induced adipogenesis.
Journal ArticleDOI
Three Dimensional Collagen Scaffold Promotes Intrinsic Vascularisation for Tissue Engineering Applications
Elsa C. Chan,Shyh Ming Kuo,Anne M. Kong,Wayne A. Morrison,Wayne A. Morrison,Wayne A. Morrison,Gregory J. Dusting,Gregory J. Dusting,Geraldine M. Mitchell,Geraldine M. Mitchell,Geraldine M. Mitchell,Shiang Y. Lim,Shiang Y. Lim,Guei-Sheung Liu +13 more
TL;DR: These collagen scaffolds are biocompatible and could be used to grow more robust vascularized tissue engineering grafts with improved the survival of implanted cells.
Journal ArticleDOI
Ocular Drug Delivery: Role of Degradable Polymeric Nanocarriers for Ophthalmic Application
TL;DR: This review summarized recent studies on sustained ocular drug/gene delivery and emphasized on the nanocarriers made by biodegradable polymers such as liposome, poly lactic-co-glycolic acid (PLGA), chitosan, and gelatin.
Journal ArticleDOI
Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expression
J Liu,X Bi,T Chen,Qunye Zhang,Shourong Wang,JJ Chiu,Guei-Sheung Liu,Yun Zhang,P Bu,Fan Jiang +9 more
TL;DR: Sirt1-mediated autophagy in ECs may be a novel mechanism by which laminar flow produces its vascular-protective actions, and it is demonstrated that flow-conditioned cells are more resistant to oxidant-induced cell injury, and this cytoprotective effect was abolished after inhibition of autophile.