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Anne-Sophie Archambault
Researcher at Laval University
Publications - 17
Citations - 319
Anne-Sophie Archambault is an academic researcher from Laval University. The author has contributed to research in topics: Biology & Chemistry. The author has an hindex of 7, co-authored 11 publications receiving 159 citations.
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Journal ArticleDOI
High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients.
Anne-Sophie Archambault,Younes Zaid,Younes Zaid,Volatiana Rakotoarivelo,Caroline Turcotte,Étienne Doré,Isabelle Dubuc,Cyril Martin,Olivier Flamand,Youssef Amar,Amine Cheikh,Hakima Fares,Amine El Hassani,Y. Tijani,Andréanne Côté,Michel Laviolette,Eric Boilard,Louis Flamand,Nicolas Flamand +18 more
TL;DR: A targeted lipidomic analysis of bronchoalveolar lavages (BALs) by tandem mass spectrometry was done on 25 healthy controls and 33 severe acute respiratory syndrome coronavirus 2 (COVID-19) patients requiring mechanical ventilation as discussed by the authors.
Journal ArticleDOI
Correlation between CCL26 production by human bronchial epithelial cells and airway eosinophils: Involvement in patients with severe eosinophilic asthma
Marie-Chantal Larose,Jamila Chakir,Anne-Sophie Archambault,Philippe Joubert,Véronique Provost,Michel Laviolette,Nicolas Flamand +6 more
TL;DR: In this paper, the authors investigated the role of CCL26 in persistent eosinophilia in patients with severe asthma despite treatment with high corticosteroid doses, and showed that CCL 26 production by BECs might be involved in persistent EosINophilia.
Journal ArticleDOI
Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils.
Anne-Sophie Archambault,Caroline Turcotte,Cyril Martin,Véronique Provost,Marie-Chantal Larose,Catherine Laprise,Jamila Chakir,Elyse Y. Bissonnette,Michel Laviolette,Ynuk Bossé,Nicolas Flamand +10 more
TL;DR: The data indicate that the best 15-lo-1 inhibitors in eosinophils are BLX3887, BLX769, NDGA and ML351 and that the synthesis of 15-LO metabolites by neutrophils does not involve the 15- LO-1 nor the phosphorylation of 5-LO on Ser-663 but is rather the consequence of 15
Journal ArticleDOI
Regulation of Eosinophil and Group 2 Innate Lymphoid Cell Trafficking in Asthma.
Marie-Chantal Larose,Anne-Sophie Archambault,Véronique Provost,Michel Laviolette,Nicolas Flamand +4 more
TL;DR: Mechanisms involved in eosinophil and ILC2 recruitment to the airways are reviewed, with an emphasis on eotaxins, other chemokines as well as their receptors, and the involvement of other chemoattractants.
Journal ArticleDOI
Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes
Caroline Turcotte,Anne-Sophie Archambault,Élizabeth Dumais,Cyril Martin,Marie-Renée Blanchet,Elyse Y. Bissonnette,Nami Ohashi,Keiko Yamamoto,Toshimasa Itoh,Michel Laviolette,Alain Veilleux,Louis-Philippe Boulet,Vincenzo Di Marzo,Nicolas Flamand +13 more
TL;DR: The data strongly indicate that human leukocytes use AA and UFAs to biosynthesize biologically significant concentrations of 2‐ AG and other MAGs and that hijacking the immune system with 2‐AG hydrolysis inhibitors might diminish inflammation in humans.