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Anne-Sophie Pierre
Researcher at University of Burgundy
Publications - 3
Citations - 180
Anne-Sophie Pierre is an academic researcher from University of Burgundy. The author has contributed to research in topics: Apoptosis & CHOP. The author has an hindex of 3, co-authored 3 publications receiving 161 citations.
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Journal ArticleDOI
Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells.
Mélaine Minville-Walz,Anne-Sophie Pierre,Laurent Pichon,Sandrine Bellenger,Cécile Fèvre,Jérôme Bellenger,Christian Tessier,Michel Narce,Mickaël Rialland +8 more
TL;DR: Results suggest that inhibition of de novo MUFA synthesis by Scd1 extinction could be a promising anti-cancer target by inducing cell death through UPR and CHOP activation.
Journal ArticleDOI
Trans-10, cis-12 conjugated linoleic acid induced cell death in human colon cancer cells through reactive oxygen species-mediated ER stress
Anne-Sophie Pierre,Mélaine Minville-Walz,Cécile Fèvre,Aziz Hichami,Joseph Gresti,Laurent Pichon,Sandrine Bellenger,Jérôme Bellenger,François Ghiringhelli,Michel Narce,Mickaël Rialland +10 more
TL;DR: It is highlighted that t10,c12 CLA exerts its cytotoxic effect through ROS generation and a subsequent ER stress-dependent apoptosis in colon cancer cells.
Journal ArticleDOI
The metabolic cascade leading to eicosanoid precursors--desaturases, elongases, and phospholipases A2--is altered in Zucker fatty rats.
Cécile Fèvre,Sandrine Bellenger,Anne-Sophie Pierre,Mélaine Minville,Jérôme Bellenger,Joseph Gresti,Mickaël Rialland,Michel Narce,Christian Tessier +8 more
TL;DR: The results suggest that the regulation of unsaturated fatty acids biosynthesis and signalling cascade could contribute to the development of liver lipid dysregulation related to metabolic syndrome and may be considered as new potential targets in such pathological conditions.