A
Annette Schwerdtfeger
Researcher at Laval University
Publications - 2
Citations - 178
Annette Schwerdtfeger is an academic researcher from Laval University. The author has contributed to research in topics: Benzopyran & Selective estrogen receptor modulator. The author has an hindex of 2, co-authored 2 publications receiving 171 citations.
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Journal ArticleDOI
(S)-(+)-4-[7-(2,2-Dimethyl-1-oxopro- poxy)-4-methyl-2-[4-[2-(1-piperidinyl)- ethoxy]phenyl]-2H-1-benzopyran-3-yl]- phenyl 2,2-Dimethylpropanoate (EM-800): A Highly Potent, Specific, and Orally Active Nonsteroidal Antiestrogen
Sylvain Gauthier,Brigitte Caron,Julie Cloutier,Yves L. Dory,Alexandre Favre,Denis Larouche,Josée Mailhot,Carl Ouellet,Annette Schwerdtfeger,Gilles Leblanc,Céline Martel,Jacques Simard,Yves Merand,Alain Bélanger,Claude Labrie,Fernand Labrie +15 more
Journal ArticleDOI
Synthesis and structure-activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution.
Sylvain Gauthier,Julie Cloutier,Yves L. Dory,Alexandre Favre,Josée Mailhot,Carl Ouellet,Annette Schwerdtfeger,Yves Merand,Céline Martel,Jacques Simard,Fernand Labrie +10 more
TL;DR: EM-652 (acolbifene) analogs have been synthesized as selective estrogen receptor modulators and 2H-1-Benzopyran 1b (EM-343, racemic form of EM-652), which contains a piperidine ring, shows the best pharmacological profile.