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Anshu Nain
Researcher at Indian Institutes of Technology
Publications - 3
Citations - 29
Anshu Nain is an academic researcher from Indian Institutes of Technology. The author has contributed to research in topics: Picornavirus & Picornaviridae. The author has an hindex of 2, co-authored 2 publications receiving 22 citations. Previous affiliations of Anshu Nain include Indian Institute of Technology Delhi.
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The C-terminal region of the non-structural protein 2B from Hepatitis A Virus demonstrates lipid-specific viroporin-like activity.
TL;DR: This study clearly establishes HAV 2B as a bona fide viroporin in the picornaviridae family, and shows that this region is capable of forming small pores in membranes and demonstrates lipid specific activity, which partially rationalizes the intracellular localization of full-length 2B.
Journal ArticleDOI
Toward development of generic inhibitors against the 3C proteases of picornaviruses.
Kamalika Banerjee,Ruchika Bhat,V. U. Bhaskara Rao,Anshu Nain,Kartik Lakshmi Rallapalli,Sohona Gangopadhyay,Ravi P. Singh,Manidipa Banerjee,Bhyravabhotla Jayaram +8 more
TL;DR: This work has targeted the 3C protease of Hepatitis A Virus, a feco‐orally transmitted virus of the family Picornaviridae, for identification of potential antivirals and identified a few compounds which could inhibit HAV 3C activity.
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Oligomers of hepatitis A virus (HAV) capsid protein VP1 generated in a heterologous expression system
TL;DR: In this paper , the authors attempted several strategies for recombinant production of one of the major capsid proteins VP1, from HAV, in the E. coli expression system, which resulted in the formation of soluble aggregates or tight association of VP1 with the bacterial chaperone GroEL.