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Anthony Absalom
Researcher at University Medical Center Groningen
Publications - 238
Citations - 9351
Anthony Absalom is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Medicine & Sedation. The author has an hindex of 45, co-authored 210 publications receiving 7369 citations. Previous affiliations of Anthony Absalom include University of Cape Town & Katholieke Universiteit Leuven.
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Journal ArticleDOI
Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial
Andrew Davidson,Nicola Disma,Jurgen C. de Graaff,Davinia E. Withington,Liam Dorris,Graham Bell,Robyn Stargatt,Robyn Stargatt,David C. Bellinger,David C. Bellinger,Tibor Schuster,Sarah J Arnup,Pollyanna Hardy,Rodney W. Hunt,Rodney W. Hunt,Michael Takagi,Gaia Giribaldi,Penelope L Hartmann,Ida Salvo,Neil S. Morton,Britta S von Ungern Sternberg,Britta S von Ungern Sternberg,Bruno Guido Locatelli,Niall C. T. Wilton,Anne M. Lynn,Joss J. Thomas,David M. Polaner,Oliver Bagshaw,Peter Szmuk,Anthony Absalom,Geoff Frawley,Charles B. Berde,Gillian D Ormond,Jacki Marmor,Mary Ellen McCann +34 more
TL;DR: This trial found no evidence that just under an hour of sevoflurane anaesthesia in infancy increases the risk of adverse neurodevelopmental outcome at two years of age compared to RA.
Journal ArticleDOI
Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine
Maud A S Weerink,Michel Struys,Michel Struys,Laura N. Hannivoort,Clemens R M Barends,Anthony Absalom,Pieter Colin,Pieter Colin +7 more
TL;DR: Dexmedetomidine as discussed by the authors is an α2-adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory function.
Journal ArticleDOI
Pharmacokinetic models for propofol—defining and illuminating the devil in the detail
TL;DR: The recently introduced open-target-controlled infusion (TCI) systems can be programmed with any pharmacokinetic model, and allow either plasma- or effect-site targeting, and the Schnider model should always be used in effect- site targeting mode.
Journal ArticleDOI
Clinical Pharmacokinetics and Pharmacodynamics of Propofol.
TL;DR: An overview of the PK and PD of propofol is provided in order to refresh readers’ knowledge of its clinical applications, while discussing the main avenues of research where significant recent advances have been made.
Journal ArticleDOI
Dissociating speech perception and comprehension at reduced levels of awareness
Matthew H. Davis,Martin R. Coleman,Anthony Absalom,Jennifer M. Rodd,Ingrid S. Johnsrude,Basil F. Matta,Adrian M. Owen,David K. Menon +7 more
TL;DR: A graded degradation of cognitive function in response to sedation such that “higher-level” semantic and mnemonic processes can be impaired at relatively low levels of sedation, whereas perceptual processing of speech remains resilient even during deep sedation.