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Anthony F. Cann
Researcher at University of California, Los Angeles
Publications - 9
Citations - 1547
Anthony F. Cann is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Metabolic engineering & Escherichia coli. The author has an hindex of 7, co-authored 9 publications receiving 1461 citations. Previous affiliations of Anthony F. Cann include University of California.
Papers
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Journal ArticleDOI
Metabolic engineering of Escherichia coli for 1-butanol production.
Shota Atsumi,Anthony F. Cann,Michael R. Connor,Claire R. Shen,Kevin M. Smith,Mark P. Brynildsen,Katherine J. Chou,Taizo Hanai,James C. Liao +8 more
TL;DR: A synthetic pathway is engineered in Escherichia coli and the production of 1-butanol is demonstrated from this non-native user-friendly host, showing promise for using E. coli for 1- butanol production.
Journal ArticleDOI
Production of 2-methyl-1-butanol in engineered Escherichia coli
Anthony F. Cann,James C. Liao +1 more
TL;DR: This work describes the first strain of E. coli developed to produce the higher alcohol and potential new biofuel 2-methyl-1-butanol (2MB), explored the biodiversity of enzymes catalyzing key parts of the isoleucine biosynthetic pathway, and knocked out competing pathways upstream of threonine production to increase its availability for further improvement of 2MB production.
Journal ArticleDOI
3-Methyl-1-butanol production in Escherichia coli: random mutagenesis and two-phase fermentation
TL;DR: A mutagenesis approach in developing a strain of Escherichia coli for the production of 3-methyl-1-butanol by leveraging selective pressure toward l-leucine biosynthesis and screening for increased alcohol production is demonstrated.
Journal ArticleDOI
Pentanol isomer synthesis in engineered microorganisms.
Anthony F. Cann,James C. Liao +1 more
TL;DR: In this article, microbial strains for 1-pentanol and 3-methyl-1-butanol were developed, as well as that for pentenol and pentanol isomers through metabolic engineering.
Patent
Biofuel production by recombinant microorganisms
James C. Liao,Shota Atsumi,Kevin M. Smith,Roa Pu Claire Shen,Anthony F. Cann,Michael R. Connor +5 more
TL;DR: In this paper, metabolically-modified microorganisms useful for producing biofuels are presented, provided that they are methods of producing high alcohols including isobutanol, 1-butanol and 1-propanol from a suitable substrate.