A
Anthony Ryan
Researcher at Dublin City University
Publications - 1
Citations - 172
Anthony Ryan is an academic researcher from Dublin City University. The author has contributed to research in topics: Acquired immune system & Pseudomembranous colitis. The author has an hindex of 1, co-authored 1 publications receiving 159 citations.
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A role for TLR4 in clostridium difficile infection and the recognition of surface layer proteins
Anthony Ryan,Mark Lynch,Sinead M. Smith,Sylvie Amu,Hendrik J. Nel,Claire E. McCoy,Jennifer K. Dowling,Eve Draper,Vincent P. O’Reilly,Ciara McCarthy,Julie B. O'Brien,Deirdre Ni Eidhin,Mary J. O'Connell,Brian Keogh,Charles Oliver Morton,Thomas R. Rogers,Padraic G. Fallon,Luke A. J. O'Neill,Dermot Kelleher,Christine E. Loscher +19 more
TL;DR: Results indicate that SLPs isolated from C. difficile can activate innate and adaptive immunity and that these effects are mediated byTLR4, with TLR4 having a functional role in experimental C.difficile infection.