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Anthony T. Yachnis
Researcher at University of Florida
Publications - 154
Citations - 7289
Anthony T. Yachnis is an academic researcher from University of Florida. The author has contributed to research in topics: Primitive neuroectodermal tumor & Magnetic resonance imaging. The author has an hindex of 44, co-authored 154 publications receiving 6604 citations. Previous affiliations of Anthony T. Yachnis include George Washington University & Children's Hospital of Philadelphia.
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Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.
Terence R. Flotte,Bruce C. Trapnell,Margaret Humphries,Brenna Carey,Roberto Calcedo,Farshid N. Rouhani,Martha Campbell-Thompson,Anthony T. Yachnis,Robert A. Sandhaus,Noel G. McElvaney,Christian Mueller,Louis M. Messina,James M. Wilson,Mark L. Brantly,David R. Knop,Guo-jie Ye,Jeffrey D. Chulay +16 more
TL;DR: It is indicated that serum levels of vector-derived normal human AAT >20 μg/ml can be achieved, and further improvements in the design or delivery of rAAV-AAT vectors will be required to achieve therapeutic target serum AAT concentrations.
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Bone marrow transdifferentiation in brain after transplantation: a retrospective study
Christopher R. Cogle,Anthony T. Yachnis,Eric D. Laywell,Dani S. Zander,John R. Wingard,Dennis A. Steindler,Edward W. Scott +6 more
TL;DR: Postnatal human neuropoiesis happens, and human haemopoietic cells can transdifferentiate into neurons, astrocytes, and microglia in a long-term setting without fusing, which could serve as a therapeutic source for long- term regenerative neuropoyingis.
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Tissue distribution of erythropoietin and erythropoietin receptor in the developing human fetus
TL;DR: The distribution of Epo and its receptor is more widespread in the developing human than was initially postulated, leading us to speculate that Epo acts in concert with somatic growth and development factors during this period of fetal development.
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"Joubert syndrome" revisited: key ocular motor signs with magnetic resonance imaging correlation
Bernard L. Maria,Karin B.N. Hoang,Ronald J. Tusa,Anthony A. Mancuso,Latif M. Hamed,Ronald G. Quisling,Martin T. Hove,Eileen B. Fennell,Margaret Booth-Jones,Deborah M. Ringdahl,Anthony T. Yachnis,Gwen Creel,Beth Frerking +12 more
TL;DR: Results indicate that Joubert syndrome results from maldevelopment of the midbrain and cerebellar vermis, producing a pathognomonic sign on MRI.
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C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD
Yuanjing Liu,Amrutha Pattamatta,Tao Zu,Tammy Reid,Olgert Bardhi,David R. Borchelt,Anthony T. Yachnis,Laura P.W. Ranum +7 more
TL;DR: A BAC mouse model of C9orf72 ALS/FTD that shows decreased survival, paralysis, muscle denervation, motor neuron loss, anxiety-like behavior, and cortical and hippocampal neurodegeneration is reported.