A
Arkajyoti Bhattacharya
Researcher at University Medical Center Groningen
Publications - 19
Citations - 147
Arkajyoti Bhattacharya is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 4, co-authored 9 publications receiving 58 citations. Previous affiliations of Arkajyoti Bhattacharya include University of Groningen.
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Journal ArticleDOI
Transcriptional effects of copy number alterations in a large set of human cancers
Arkajyoti Bhattacharya,Rico D. Bense,Carlos G. Urzua-Traslavina,Elisabeth G.E. de Vries,Marcel A. T. M. van Vugt,Rudolf S N Fehrmann +5 more
TL;DR: The authors present transcriptional adaptation to CNA (TACNA) profiling; a tool to extract the transcriptional effect of CNAs from expression data without requiring paired CNA profiles, and provide a novel tool to gain insight into how CNAs drive tumor behavior via altered expression levels.
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Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors
Yannick P Kok,Sergi Guerrero Llobet,Pepijn M Schoonen,Marieke Everts,Arkajyoti Bhattacharya,Rudolf S N Fehrmann,Nathalie van den Tempel,Marcel A. T. M. van Vugt +7 more
TL;DR: The data suggest that Cyclin E1 overexpression can be used to select patients for treatment with replication checkpoint inhibitors and point to mitotic catastrophe as an underlying mechanism.
Journal ArticleDOI
Improving gene function predictions using independent transcriptional components
Carlos G. Urzua-Traslavina,Vincent Christiaan Leeuwenburgh,Vincent Christiaan Leeuwenburgh,Arkajyoti Bhattacharya,Stefan Loipfinger,Marcel A. T. M. van Vugt,Elisabeth G.E. de Vries,Rudolf S N Fehrmann +7 more
TL;DR: In this article, the authors use a consensus independent component analysis and guilt-by-association approach to predict over 23,000 functional groups comprised of over 55,000 coding and non-coding transcripts using publicly available transcriptomic profiles.
Journal ArticleDOI
Validation and update of a lymph node metastasis prediction model for breast cancer.
Si-Qi Qiu,Merel Aarnink,Marissa C. van Maaren,Monique D. Dorrius,Arkajyoti Bhattacharya,Jeroen Veltman,Caroline A H Klazen,Jan H. Korte,Susanne H. Estourgie,Pieter Ott,W. Kelder,Huan Cheng Zeng,Hendrik Koffijberg,Guo-Jun Zhang,Gooitzen M. van Dam,Sabine Siesling +15 more
TL;DR: The updated models resulted in more accurate ALN metastasis prediction and could be useful preoperative tools in selecting low-risk patients for omission of axillary surgery.
Journal ArticleDOI
Immunogenicity after second and third mRNA-1273 vaccination doses in patients receiving chemotherapy, immunotherapy, or both for solid tumours
Sjoukje F. Oosting,Astrid A.M. van der Veldt,Rudolf S N Fehrmann,Corine H. GeurtsvanKessel,Rob van Binnendijk,Anne-Marie C. Dingemans,Egbert F. Smit,T. Jeroen N. Hiltermann,Gerco den Hartog,M. Jalving,Tatjana T Westphal,Arkajyoti Bhattacharya,F. de Wilt,Annemarie Boerma,L. van Zijl,Guus F. Rimmelzwaan,Pia Kvistborg,Cécile A. C. M. van Els,Nynke Y. Rots,Debbie van Baarle,John B. A. G. Haanen,Elisabeth G.E. de Vries +21 more