A
Armin Scheffler
Publications - 31
Citations - 1133
Armin Scheffler is an academic researcher. The author has contributed to research in topics: Betulin & Oleanolic acid. The author has an hindex of 11, co-authored 26 publications receiving 961 citations.
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Journal ArticleDOI
Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.
TL;DR: Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and stem bark display various pharmacological effects while being devoid of prominent toxicity and are promising leading compounds for the development of new multi-targeting bioactive agents.
Journal ArticleDOI
Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L
TL;DR: The triterpene acid content of neutral plant extracts above the solubility limit could be due to interactions with biocolloids, and different mechanisms of the dissolution at pH 7.3 and pH 10.2 are discussed.
Journal ArticleDOI
Physical, chemical and pharmacological characterization of a new oleogel-forming triterpene extract from the outer bark of birch (betulae cortex).
Melanie N. Laszczyk,Sebastian Jäger,Birgit Simon-Haarhaus,Armin Scheffler,Christoph M. Schempp +4 more
TL;DR: Experimental data support the notion from a previous clinical study that TE from the outer bark of birch might represent a new tool for the topical treatment of skin cancer and skin cancer precursors like actinic keratoses.
Journal ArticleDOI
Treatment of actinic keratoses with a novel betulin-based oleogel. A prospective, randomized, comparative pilot study.
Constance Huyke,Juliane Reuter,Mirko Rödig,Astrid Kersten,Melanie N. Laszczyk,Armin Scheffler,Dorothee Nashan,Christoph M. Schempp +7 more
TL;DR: Betulin‐based oleogel prepared from a standardized triter‐pene dry extract from birch bark represents a new topical agent with anti‐inflammatory and anti‐tumor potential.
Journal ArticleDOI
Triterpenes Promote Keratinocyte Differentiation In Vitro, Ex Vivo and In Vivo: A Role for the Transient Receptor Potential Canonical (subtype) 6
Ute Woelfle,Melanie N. Laszczyk,Margarethe Kraus,Kristina Leuner,Astrid Kersten,B. Simon-Haarhaus,Armin Scheffler,Stefan F. Martin,Walter E. Müller,Dorothee Nashan,Christoph M. Schempp +10 more
TL;DR: The data indicate that TE promotes keratinocyte differentiation in vitro and in vivo, and seems to be mediated at least in part by TRPC6.