A
Arunas Savickas
Researcher at Lithuanian University of Health Sciences
Publications - 27
Citations - 1024
Arunas Savickas is an academic researcher from Lithuanian University of Health Sciences. The author has contributed to research in topics: Toxicity & Propolis. The author has an hindex of 12, co-authored 27 publications receiving 567 citations.
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Journal ArticleDOI
Flavonoids as Anticancer Agents
TL;DR: Flavonoids have dual action regarding ROS homeostasis—they act as antioxidants under normal conditions and are potent pro-oxidants in cancer cells triggering the apoptotic pathways and downregulating pro-inflammatory signaling pathways.
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Alternative preparation of propolis extracts: comparison of their composition and biological activities
Loreta Kubiliene,Virginija Laugaliene,Alvydas Pavilonis,Audrius Maruška,Daiva Majiene,Karolina Barcauskaite,Raimondas Kubilius,Giedre Kasparaviciene,Arunas Savickas +8 more
TL;DR: Nonethanolic solvent complex and the effect of higher temperature allows more effective extraction of active compounds from propolis, which has radical scavenging and antimicrobial activity.
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Uncoupling and antioxidant effects of ursolic acid in isolated rat heart mitochondria.
Julius Liobikas,Daiva Majiene,Sonata Trumbeckaite,Lolita Kursvietiene,Ruta Masteiková,Dalia M. Kopustinskiene,Arunas Savickas,Jurga Bernatoniene +7 more
TL;DR: The present results indicate that ursolic acid has potential use as a cardioprotective compound and induces a statistically significant uncoupling of oxidative phosphorylation.
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Effect of Ginkgo biloba extract on the rat heart mitochondrial function
Sonata Trumbeckaite,Jurga Bernatoniene,Daiva Majiene,Valdas Jakštas,Arunas Savickas,Adolfas Toleikis +5 more
TL;DR: The data showed that 0.5 microl/ml of GE had no effect on the State 2 respiration rate of mitochondria with all used substrates: pyruvate+malate, succinate and palmitoyl-L-carnitine, and other biologically active compounds of GE have to be taken into account in future studies.
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The effect of crataegus fruit extract and some of its flavonoids on mitochondrial oxidative phosphorylation in the heart.
Jurga Bernatoniene,Sonata Trumbeckaite,Daiva Majiene,Rasa Baniene,Giedre Baliutyte,Arunas Savickas,Adolfas Toleikis +6 more
TL;DR: An oxygraphic investigation of the effect of CE and its several pure flavonoids on isolated rat heart mitochondria respiring and its uncoupling effects on mitochondrial respiration found that the highest CE concentration slightly reduced the maximal ADP‐stimulated and uncoupled respiration.