Åsa Edvinsson

TL;DR: The expression pattern of ACE2 across > 150 different cell types corresponding to all major human tissues and organs based on stringent immunohistochemical analysis constitutes an important resource for further studies on SARS‐CoV‐2 host cell entry, to understand the biology of the disease and to aid in the development of effective treatments to the viral infection.

TL;DR: Investigation of how different fixatives influence protein recognition by immunodetection methods in tissues, cell preparations, and protein lysates, as compared with formalin found morphological resolution and immunoreactivity were superior in tissues fixed with aldehyde-based fixatives, whereas the use of non-aldehyde– based fixatives can be advantageous in obtaining high protein yield for Western blot analysis.

TL;DR: It is revealed that the majority of inflammatory and anti-inflammatory markers decreased from pregnancy to postpartum, and only a few increased, which clearly reflects the tremendous change in the immune system in the pregnancy toPostpartum transition.

TL;DR: The results do not support the use of a single inflammation marker in late pregnancy for assessing risk of postpartum depression, but theUse of STAM-BP or the novel notion of a summary inflammation variable developed in this work might be used in combination with other biological markers in the future.

TL;DR: Women with antenatal depression or on SSRI treatment have lower levels of a number of peripheral inflammatory markers than healthy pregnant controls, which could be due to dysregulated switch to the pro-M2 milieu that characterizes normal third trimester pregnancy.