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Asawer Hassan Najm
Researcher at University of Kufa
Publications - 6
Citations - 20
Asawer Hassan Najm is an academic researcher from University of Kufa. The author has contributed to research in topics: Transferrin saturation & Internal medicine. The author has an hindex of 2, co-authored 5 publications receiving 11 citations.
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Journal ArticleDOI
Major Depression in Children with Transfusion-Dependent Thalassemia Is Strongly Associated with the Combined Effects of Blood Transfusion Rate, Iron Overload, and Increased Pro-inflammatory Cytokines.
Hussein Kadhem Al-Hakeim,Asawer Hassan Najm,Arafat Hussein Al-Dujaili,Michael Maes,Michael Maes,Michael Maes +5 more
TL;DR: Blood transfusions may be causally related to MDLE in TDT children and their effects are in part mediated by increased iron overload and the consequent immune-inflammatory response.
Journal ArticleDOI
Construction of an exposure-pathway-phenotype in children with depression due to transfusion-dependent thalassemia: Results of (un)supervised machine learning.
Hussein Kadhem Al-Hakeim,Asawer Hassan Najm,Shatha Rouf Moustafa,Michael Maes,Michael Maes,Michael Maes +5 more
TL;DR: The nomological network combining exposure, pathways and behavioral phenome manifestations provides an index of overall severity and disease risk and, therefore, constitutes a new drug target, indicating that iron overload and immune activation should be targeted to treat depression due to TDT.
Posted ContentDOI
Construction of an Exposure-Pathway-Phenotype in Children with Depression due to Transfusion-Dependent Thalassemia: Results of (Un)supervised Machine Learning
Hussein Kadhem Al-Hakeim,Asawer Hassan Najm,Shatha Rouf Moustafa,Michael Maes,Michael Maes,Michael Maes +5 more
TL;DR: In this article, a pathway-phenotype which combines iron overload and neuro-immune biomarkers with depressive symptom subdomains in transfusion dependent thalassemia (TDT) patients was constructed.
Posted ContentDOI
Major Depression in Children with β-Thalassemia Major is Strongly Associated with the Number of Blood Transfusions, Iron Overload and Increased Levels of Interleukin-1β
TL;DR: It is suggested that not only IO and its consequences including inflammation and ferroptosis, but also other factors related to the number of transfusions may cause MDD including psychosocial stressors.
Journal ArticleDOI
Role of Glucagon-Like Peptide-1 in Appetite Regulation in Patients with Morbid Obesity and Leptin Resistance
TL;DR: Findings of using GLP-1 as an appetite regulator for the morbidly obese patients and have leptin resistance (resistance to its action in appetite regulation), presented here, should provide a valuable information for further experimental investigations.