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Athanasios Valavanidis
Researcher at National and Kapodistrian University of Athens
Publications - 37
Citations - 7596
Athanasios Valavanidis is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Radical & Oxidative stress. The author has an hindex of 22, co-authored 37 publications receiving 6464 citations.
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Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants.
TL;DR: Current knowledge and advances in the understanding of oxidative processes in biological systems are summarized and this knowledge is extended to specific applications in aquatic organisms because of their sensitivity to oxidative pollutants, their filtration capacity, and their potential for environmental toxicology studies.
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8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis.
TL;DR: The biomarker 8-OHdG or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis and has been used to estimate the DNA damage in humans after exposure to cancer-causing agents.
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Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms
TL;DR: The evaluation of most of these studies shows that the smaller the size of PM the higher the toxicity through mechanisms of oxidative stress and inflammation, and Associations between chemical compositions and particle toxicity tend to be stronger for the fine and ultrafine PM size fractions.
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Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms
TL;DR: The role of ROS and oxidative stress in the production of mediators of pulmonary inflammation and mechanisms of carcinogenesis are presented and pulmonary cancer initiation and promotion is linked to a series of biochemical pathways of oxidative stress.
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Tobacco smoke: involvement of reactive oxygen species and stable free radicals in mechanisms of oxidative damage, carcinogenesis and synergistic effects with other respirable particles.
TL;DR: Results showed that the semiquinone radical system has the potential for redox recycling and oxidative action and proved that aqueous cigarette tar (ACT) solutions can generate adducts with DNA nucleobases, particularly the mutagenic 8-hydroxy-2’-deoxyguanosine (a biomarker for carcinogenesis).