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Audrey Mohr
Researcher at University of Paris
Publications - 13
Citations - 1122
Audrey Mohr is an academic researcher from University of Paris. The author has contributed to research in topics: Immune system & Antibody. The author has an hindex of 9, co-authored 12 publications receiving 604 citations. Previous affiliations of Audrey Mohr include French Institute of Health and Medical Research.
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Journal ArticleDOI
IgA dominates the early neutralizing antibody response to SARS-CoV-2.
Delphine Sterlin,Delphine Sterlin,Alexis Mathian,Makoto Miyara,Audrey Mohr,François Anna,Laetitia Claër,Paul Quentric,Jehane Fadlallah,Hervé Devilliers,Pascale Ghillani,Cary Gunn,Rick Hockett,Sasi Mudumba,Amélie Guihot,Charles Edouard Luyt,Julien Mayaux,Alexandra Beurton,Salma Fourati,Timothée Bruel,Olivier Schwartz,Jean Marc Lacorte,Hans Yssel,Christophe Parizot,Karim Dorgham,Pierre Charneau,Zahir Amoura,Guy Gorochov +27 more
TL;DR: Specific IgA serum concentrations decreased notably 1 month after the onset of symptoms, but neutralizing IgA remained detectable in saliva for a longer time (days 49 to 73 post-symptoms).
Posted ContentDOI
IgA dominates the early neutralizing antibody response to SARS-CoV-2
Delphine Sterlin,Delphine Sterlin,Alexis Mathian,Makoto Miyara,Audrey Mohr,François Anna,Laetitia Claër,Paul Quentric,Jehane Fadlallah,Pascale Ghillani,Cary Gunn,Rick Hockett,Sasi Mudumba,Amélie Guihot,Charles-Edouard Luyt,Julien Mayaux,Alexandra Beurton,Salma Fourati,Jean-Marc Lacorte,Hans Yssel,Christophe Parizot,Karim Dorgham,Pierre Charneau,Zahir Amoura,Guy Gorochov +24 more
TL;DR: Interestingly, early SARS-CoV-2-specific humoral responses were found to be typically dominated by antibodies of the IgA isotype, and whether vaccine regimens should consider boosting a potent, although, at least in blood, fading IgA response is challenged.
Journal ArticleDOI
Human FOXP3+ T regulatory cell heterogeneity.
TL;DR: It is discussed here how Treg cell subsets can be differentiated phenotypically, functionally and developmentally in humans and can therefore be differentially targeted in the management of autoimmune diseases or in cancer.
Journal ArticleDOI
Human regulatory B cells control the TFH cell response
Achouak Achour,Quentin Simon,Audrey Mohr,Jean-François Séité,Pierre Youinou,Boutahar Bendaoud,Ibtissem Ghedira,Jacques-Olivier Pers,Christophe Jamin +8 more
TL;DR: Novel observations demonstrate a role for the Breg cell in germinal center reactions and suggest that deficient activities might impair the TFH cell–dependent control of humoral immunity and might lead to the development of aberrant autoimmune responses.
Journal ArticleDOI
The role of FOXP3+ regulatory T cells in human autoimmune and inflammatory diseases.
TL;DR: Conflicting data regarding whether Treg cells are more effectual at preventing the initiation of autoimmunity, ameliorating disease progression or curing autoIMmunity itself are discussed.