抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Data Mining Practical Machine Learning Tools and Techniques

An overview of the self-organizing map algorithm, on which the papers in this issue are based, is presented in this article.

The Self-Organizing Map

Annals of physics

relationship. All subsequent studies confirmed it (see for example King and Levine, 1993, and the review in: Pagano, 1993). Goldsmith used a sample of 35 countries for the period between 1860 and 1963 to show the relationship between income and financial depth measured by the ratio between bank's assets and GDP. He also showed that in periods of rapid growth, financial depth grows faster than income. More details about measuring financial depth can be found in this paper. FINANCIAL DEVELOPMENT AND ECONOMIC GROWTH Velimir Šonje

/pdf/financial-development-and-economic-growth-1933kuo17q.pdf

Financial development and economic growth

The inefficiency of Bitcoin revisited: A dynamic approach

Fil: Fernandez, Aurelio. Universitat Rovira I Virgili; Espana. Consejo Nacional de Investigaciones Cientificas y Tecnicas; Argentina

Some stylized facts of the Bitcoin market

Blockchain technology, and more specifically Bitcoin (one of its foremost applications), have been receiving increasing attention in the scientific community. The first publications with Bitcoin as a topic, can be traced back to 2012. In spite of this short time span, the production magnitude (1162 papers) makes it necessary to make a bibliometric study in order to observe research clusters, emerging topics, and leading scholars. Our paper is aimed at studying the scientific production only around bitcoin, excluding other blockchain applications. Thus, we restricted our search to papers indexed in the Web of Science Core Collection, whose topic is "bitcoin". This database is suitable for such diverse disciplines such as economics, engineering, mathematics, and computer science. This bibliometric study draws the landscape of the current state and trends of Bitcoin-related research in different scientific disciplines.

A bibliometric analysis of Bitcoin scientific production

Fil: Zunino, Luciano Jose. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - La Plata. Centro de Investigaciones Opticas. Provincia de Buenos Aires. Gobernacion. Comision de Investigaciones Cientificas. Centro de Investigaciones Opticas. Universidad Nacional de La Plata. Centro de Investigaciones Opticas; Argentina. Universidad Nacional de La Plata. Facultad de Ingenieria; Argentina

/pdf/on-the-efficiency-of-sovereign-bond-markets-23ul7m8s3u.pdf

Aurelio F. Bariviera

Papers

The inefficiency of Bitcoin revisited: A dynamic approach

Some stylized facts of the Bitcoin market

A bibliometric analysis of Bitcoin scientific production

On the efficiency of sovereign bond markets

A bibliometric analysis of bitcoin scientific production