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Axel Becker
Researcher at Martin Luther University of Halle-Wittenberg
Publications - 36
Citations - 2231
Axel Becker is an academic researcher from Martin Luther University of Halle-Wittenberg. The author has contributed to research in topics: Vascular endothelial growth factor & Tumor hypoxia. The author has an hindex of 18, co-authored 35 publications receiving 2135 citations.
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Journal ArticleDOI
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
Marianne Nordsmark,Søren M. Bentzen,Volker Rudat,David M. Brizel,Eric Lartigau,Peter Stadler,Axel Becker,Markus Adam,Michael Molls,Juergen Dunst,David J. Terris,Jens Overgaard +11 more
TL;DR: Evidence is provided that tumor hypoxia is associated with a poor prognosis in patients with advanced head and neck cancer.
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Influence of the hypoxic subvolume on the survival of patients with head and neck cancer.
Peter Stadler,Axel Becker,Horst Jürgen Feldmann,Gabriele Hänsgen,Jürgen Dunst,Florian Würschmidt,Michael Molls +6 more
TL;DR: It is suggested that the total amount of hypoxic tissue, as determined by the hypoxic subvolume, influences the prognosis of patients suffering from SCCHN and confirms the statements of previous studies that low pretherapy pO2-values indicate a worse prognosis.
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Severe anemia is associated with poor tumor oxygenation in head and neck squamous cell carcinomas.
Axel Becker,Peter Stadler,Robert S. Lavey,Gabriele Hänsgen,Thomas Kuhnt,C. Lautenschläger,Horst Jürgen Feldmann,Michael Molls,Jürgen Dunst +8 more
TL;DR: The data suggest that a low Hb concentration and cigarette smoking contribute to inadequate oxygenation of SCCHN and thus for increased radioresistance and Hb correction and abstinence from smoking may significantly improve tumor oxygenation.
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Oxygenation of squamous cell carcinoma of the head and neck: comparison of primary tumors, neck node metastases, and normal tissue
Axel Becker,Gabriele Hänsgen,Marc Bloching,Christian Weigel,Christine Lautenschläger,Jürgen Dunst +5 more
TL;DR: Primary tumors and their regional lymph node metastases in advanced squamous cell carcinoma of the head and neck show comparable patterns of oxygenation in terms of the median pO2 and the proportion of hypoxic measurements, and it is suggested that measurements in any anatomic site would be sufficient to estimate a tumor's oxygenation status.
Journal ArticleDOI
Predictive value of the tumor oxygenation by means of pO2 histography in patients with advanced head and neck cancer.
Volker Rudat,Peter Stadler,Axel Becker,Bernhard Vanselow,Andreas Dietz,Michael Wannenmacher,Michael Molls,Jürgen Dunst,Horst Jürgen Feldmann +8 more
TL;DR: The data confirm the influence of the tumor oxygenation on the prognosis of patients with squamous cell carcinoma of the head and neck after radiotherapy and suggest that the pO2 histography alone is not sufficient to be used as a predictive test to successfully select patients for treatment alternatives.