A
Axel Fischer
Researcher at Charité
Publications - 110
Citations - 5840
Axel Fischer is an academic researcher from Charité. The author has contributed to research in topics: Substance P & Vasoactive intestinal peptide. The author has an hindex of 42, co-authored 109 publications receiving 5518 citations. Previous affiliations of Axel Fischer include University of Giessen & Free University of Berlin.
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Journal ArticleDOI
The diagnosis and management of chronic cough
Alyn H. Morice,Giovanni A. Fontana,A. R. A. Sovijarvi,Massimo Pistolesi,Kian Fan Chung,John Widdicombe,F. O'Connell,Pierangelo Geppetti,Lars Grönke,J. C. De Jongste,Maria G. Belvisi,Peter V. Dicpinigaitis,Axel Fischer,Lorcan McGarvey,W. J. Fokkens,Jack A Kastelik +15 more
TL;DR: These guidelines aim to distil the lessons from these reports and provide a framework for a logical care pathway for patients with this highly disabling symptom.
Journal ArticleDOI
Increased Expression of Transient Receptor Potential Vanilloid-1 in Airway Nerves of Chronic Cough
David A. Groneberg,Akio Niimi,Q. Thai Dinh,Borja G. Cosío,Mark Hew,Axel Fischer,K. Fan Chung +6 more
TL;DR: There was a significant correlation between capsaicin tussive response and the number of TRPV-1-positive nerves within the patients with cough, indicating that TRPVs may contribute to an enhanced cough reflex and the cough response in chronic persistent cough of diverse causes.
Journal ArticleDOI
Fundamentals of pulmonary drug delivery.
TL;DR: The nature of aerosolized drugs, characteristics of delivery systems and the depositional and pulmonary clearance mechanisms display major targets to optimize pulmonary drug delivery, and the future characterization of pulmonary drug transport pathways can lead to new strategies in aerosol drug therapy.
Journal ArticleDOI
Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways
Petra C. Arck,Bori Handjiski,Eva M.J. Peters,Anita Peter,Evelin Hagen,Axel Fischer,Burghard F. Klapp,Ralf Paus +7 more
TL;DR: It is shown that psychoemotional stress indeed alters actual hair follicle (HF) cycling in vivo, ie, prematurely terminates the normal duration of active hair growth (anagen) in mice, providing the first solid pathophysiological mechanism for how stress may actually cause telogen effluvium.
Journal ArticleDOI
Occupational medicine and toxicology
David A. Groneberg,Axel Fischer +1 more
TL;DR: The launch of the Journal of Occupational Medicine and Toxicology will aid in the advance of these important areas of research bringing together multi-disciplinary research findings.