Babetta L. Marrone

TL;DR: Results obtained with normal human cells are similar to those of other investigators who observed excessive SCEs in immortalized rodent cells beyond that which could be attributed exclusively to nuclear traversals by alpha particles, and point to the existence of an alternative, extranuclear target through which alpha particles cause DNA damage, as detected by SCE analysis.

TL;DR: A laser based technique for the rapid sequencing of large fragments of DNA based upon the detection of single, fluorescently tagged nucleotides cleaved from a single DNA fragment which is orders of magnitude faster than existing methods.

TL;DR: It is suggested that progesterone-sensitive neural systems operate with a precision that is attributable more to interneuronal channeling of information to or from estrogen-sensitive areas than to intranuclear programming of biochemical events.

TL;DR: Large, fluorescently stained restriction fragments of lambda phage DNA are sized by passing individual fragments through a focused continuous wave laser beam in an ultrasensitive flow cytometer at a rate of 60 fragments per second, which can potentially analyze large fragments with better resolution and accuracy than with gel-based electrophoresis.

TL;DR: This work has developed a sensitive and rapid flow cytometry-based assay for the multiplexed analysis of SNPs based on polymerase-mediated primer extension, or minisequencing, using microspheres as solid supports, and genomic analysis using multiplexing microsphere arrays (GAMMArrays), enables the simultaneous analysis of dozens, and potentially hundreds ofSNPs per sample.