B
Balazs Gyorffy
Researcher at Semmelweis University
Publications - 130
Citations - 7493
Balazs Gyorffy is an academic researcher from Semmelweis University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 38, co-authored 129 publications receiving 5912 citations. Previous affiliations of Balazs Gyorffy include Eötvös Loránd University & Humboldt University of Berlin.
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Journal ArticleDOI
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients.
Balazs Gyorffy,András Lánczky,Aron Charles Eklund,Carsten Denkert,Jan Budczies,Qiyuan Li,Zoltan Szallasi,Zoltan Szallasi +7 more
TL;DR: An online tool to draw survival plots, which can be used to assess the relevance of the expression levels of various genes on the clinical outcome both in untreated and treated breast cancer patients, and which validated the capability of microarrays to determine estrogen receptor status in 1,231 patients.
Posted ContentDOI
Pancancer survival analysis of cancer hallmark genes
TL;DR: The aim of this study was to estimate the prognostic effect of the established cancer hallmark genes in multiple distinct cancer types and to help to prioritize future targeted therapy development in different types of solid tumors.
Journal ArticleDOI
Jetset: selecting the optimal microarray probe set to represent a gene
Qiyuan Li,Nicolai Juul Birkbak,Balazs Gyorffy,Zoltan Szallasi,Zoltan Szallasi,Aron Charles Eklund +5 more
TL;DR: This method provides a simple, unambiguous mapping to allow assessment of the expression levels of specific genes of interest and evaluated concordance between protein measurements and gene expression values.
Posted ContentDOI
TNMplot.com: a web tool for the comparison of gene expression in normal, tumor and metastatic tissues
Aron Bartha,Balazs Gyorffy +1 more
TL;DR: An integrated database using available transcriptome-level datasets and a web-platform enabling mining of this database by comparing normal, tumor and metastatic data across all genes in real time are established.
Journal ArticleDOI
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities
Donald C. Porter,Elena Farmaki,Serena Altilia,Gary P. Schools,Deborah K. West,Mengqian Chen,Bey-Dih Chang,Anatoliy T. Puzyrev,Chang-uk Lim,Rebecca Rokow-Kittell,Lawrence T. Friedhoff,Athanasios G. Papavassiliou,S Kalurupalle,Gregory Hurteau,Jun Shi,Phil S. Baran,Balazs Gyorffy,Mark P. Wentland,Eugenia V. Broude,Hippokratis Kiaris,Igor B. Roninson +20 more
TL;DR: Microarray data analysis revealed striking correlations between CDK8 expression and poor survival in breast and ovarian cancers, and small-molecule compounds that inhibit damage-induced transcription downstream of p21 offered a promising approach to increasing the efficacy of cancer chemotherapy.