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Banu S. Zolnik
Researcher at Center for Drug Evaluation and Research
Publications - 4
Citations - 878
Banu S. Zolnik is an academic researcher from Center for Drug Evaluation and Research. The author has contributed to research in topics: New product development & Drug delivery. The author has an hindex of 3, co-authored 4 publications receiving 741 citations.
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Minireview: Nanoparticles and the Immune System
TL;DR: In this paper, a review of observations on nanoparticle-mediated immunostimulation and immunosuppression, focusing on possible theories regarding how manipulation of particle physicochemical properties can influence their interaction with immune cells to attain desirable immunomodulation and avoid undesirable immunotoxicity.
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Regulatory perspective on the importance of ADME assessment of nanoscale material containing drugs
Banu S. Zolnik,Nakissa Sadrieh +1 more
TL;DR: The importance of long-term biodistribution and mass balance studies to understand the nanoparticle accumulation profile which may help to assess the safety and efficacy of the nanomaterial containing drug products is underlined.
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Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality: A Workshop Summary Report
Amitava Mitra,Sandra Suarez-Sharp,Xavier Pepin,Talia Flanagan,Yang Zhao,Evangelos Kotzagiorgis,Neil Parrott,Satish Sharan,Christophe Tistaert,Tycho Heimbach,Banu S. Zolnik,Erik Sjögren,Fang Wu,Om Anand,Shefali Kakar,Min Li,Shereeni Veerasingham,Shinichi Kijima,Gustavo Mendes Lima Santos,Baoming Ning,Kimberly Raines,Greg Rullo,Haritha Mandula,Poonam Delvadia,Jennifer B. Dressman,Paul A. Dickinson,Andrew Babiskin +26 more
TL;DR: Case studies from US FDA, EMA and pharmaceutical industry on applications of PBBM in drug product quality are summarized which include 1) regulatory agency's perspectives on establishing the safe space and achieving study waivers, and 2) model-informed risk assessment on the effects of acid reducing agents.
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Assessment of Applications of Design of Experiments in Pharmaceutical Development for Oral Solid Dosage Forms
TL;DR: An overview of how DoE is being applied to assist pharmaceutical development in New Drug application and Abbreviated New Drug Application (ANDA) submissions for oral solid dosage forms is obtained.