Showing papers by "Bao Yang published in 2015"
TL;DR: Biotransformation is a promising alternative to solve the problem of low abundance in nature and complicated to be chemically synthesized, which limits the applications in dietary supplements and medicines.
Abstract: Prenylated flavonoids have attracted much attention as a novel type of nutraceuticals in late years. The main structural characteristics and biological activities of prenylated flavonoids are reviewed in this paper. Usually prenylated flavonoids have a low abundance in nature and are complicated to be chemically synthesized, which limits the applications in dietary supplements and medicines. Biotransformation is a promising alternative to solve this problem due to the advantages of high specificity, easy manipulation and good productivity. The key to this technique is to find an effective flavonoid prenyltransferase. Detailed information regarding biotransformation and flavonoid prenyltransferase is reviewed in this paper.
120 citations
TL;DR: The protein of defatted walnut meal was subjected to enzymatic hydrolysis by pancreatin, and the hydrolysate was found to possess excellent antioxidant capacities, and could scavenge total reactive oxygen species in rat pheochromocytoma cell line.
Abstract: Defatted walnut (Juglans Sigillata Dode) meal (DWM) is the main by-product after oil extraction of walnut seed, which contains 40–45% proteins with abundant essential amino acids. In this research, the protein of defatted walnut meal was subjected to enzymatic hydrolysis by pancreatin. The hydrolysate was found to possess excellent antioxidant capacities. Also, high cytoprotective activities against H2O2-induced oxidative damage to PC12 cells were observed, with 83% cell viability at 0.1 mg/mL of peptides, and no cytotoxicity was detected against native PC12 cells. The peptides could scavenge total reactive oxygen species in rat pheochromocytoma cell line. Defatted walnut meal protein hydrolysates (DWMPH) were isolated and purified by gel filtration chromatography and reverse phase high performance liquid chromatography. By electron spray ionization-tandem mass spectrometry (ESI-MS/MS), the chemical structures of fourteen antioxidant peptides from two fractions were identified, and all of them were novel peptides were found from walnut protein hydrolysate.
74 citations
TL;DR: The results indicated that cinnamtannin B1 was a potent cancer cell proliferation inhibitor and a good intracellular antioxidant.
59 citations
TL;DR: The overall-acceptability of organic tofu prepared with MgCl2 combined with guar gum or gypsum was almost the same as conventional tofu made with gymsum while having more beany-flavour.
55 citations
TL;DR: Principal component analysis revealed the principal bioactive compounds with significant level variations between samples, and these principal chemicals could be used for quality judgment of P. tenuifolia root, instead of measuring the levels of all compositional compounds.
13 citations