B
Barbara Seliger
Researcher at Martin Luther University of Halle-Wittenberg
Publications - 258
Citations - 9543
Barbara Seliger is an academic researcher from Martin Luther University of Halle-Wittenberg. The author has contributed to research in topics: Immune system & Human leukocyte antigen. The author has an hindex of 45, co-authored 222 publications receiving 7324 citations. Previous affiliations of Barbara Seliger include Wittenberg University & Fraunhofer Society.
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Journal ArticleDOI
Granulocyte-to-dendritic cell-ratio as marker for the immune monitoring in patients with renal cell carcinoma
TL;DR: Granulocyte/DC ratio may serve as a new putative biomarker for the immune monitoring of tumor patients and comparison of both ratios before and after tumor resection in the two groups “open surgery” and “laparoscopy” could demonstrate the suitability of granulocyte-to-DC ratio as a marker for immune monitoring.
Journal ArticleDOI
Expression and function of CTLA4 in melanoma.
TL;DR: The aim of this study was to determine the expression and function of CTLA4 in 60 human tumour cells of distinct origin and to establish anti-CTLA4 antibodies in vitro.
Journal ArticleDOI
A novel approach for HLA-A typing in formalin-fixed paraffin-embedded-derived DNA
Lisa Villabona,Daniel A Leon Rodriguez,Emilia Andersson,Barbara Seliger,Tina Dalianis,Giuseppe Masucci +5 more
TL;DR: The amplification of the most polymorphic exons of HLA-A was a successful alternative when DNA quality prevented positive results with previously described methods, and has thus potential to be used in several fields such as the clinic, research, and forensic science.
Book ChapterDOI
Identification of Immune Modulatory miRNAs by miRNA Enrichment via RNA Affinity Purification.
TL;DR: A detailed protocol for construct preparation, RNA immobilization via MS2BP-MBP to beads, miRNA enrichment, and elution followed by analysis of the obtained miRNA candidates via qRT-PCR is presented.
Journal ArticleDOI
Altered Spatial Composition of the Immune Cell Repertoire in Association to CD34+ Blasts in Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemia.
Marcus Bauer,Christoforos Vaxevanis,Haifa Kathrin Al-Ali,Nadja Jaekel,Christin Naumann,Judith Schaffrath,Achim Rau,Barbara Seliger,Claudia Wickenhauser +8 more
TL;DR: The relationship between spatial immune cell distribution within the bone marrow (BM) in relation to genetic features and the course of disease has not been analyzed in detail as mentioned in this paper, however, the authors of this paper focus on the spatial distribution of the immune cells in the 10 μm area around CD34+ hematopoietic cells.