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Barry S. Winkler
Researcher at University of Rochester
Publications - 49
Citations - 3244
Barry S. Winkler is an academic researcher from University of Rochester. The author has contributed to research in topics: Glutathione & Glycolysis. The author has an hindex of 26, co-authored 49 publications receiving 3147 citations. Previous affiliations of Barry S. Winkler include Wayne State University & Oakland University.
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Journal Article
Oxidative damage and age-related macular degeneration.
TL;DR: While all these models provide undisputed evidence of oxidative damage to the retinal pigment epithelium and the choriocapillaris, it is still unclear at this time what the precise linkage is between oxidation-induced events and the onset and progression of AMD.
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The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective.
TL;DR: The evidence for and the evidence against the presence of the enzyme dehydroascorbate reductase in animal cells is outlined in a balanced way in an attempt to make sense of this continuing controversy.
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Retinal light damage: Practical and theoretical considerations
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Unequivocal evidence in support of the nonenzymatic redox coupling between glutathione/glutathione disulfide and ascorbic acid/dehydroascorbic acid
TL;DR: It is shown that there is an equimolar production of GSSG and ascorbic acid from GSH and DHA and that the decrease in GSH is stoichiometrically related to the increase in the concentration of G SSG.
Journal Article
Energy metabolism in human retinal Müller cells.
TL;DR: C cultured Müller cells obtain their ATP principally from glycolysis and have a low rate of oxygen consumption, which may spare oxygen for retinal neurons, particularly in the inner nuclear and ganglion cell layers under normal physiological conditions.