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Basira Najafzadeh

Researcher at University of Tabriz

Publications -  9
Citations -  125

Basira Najafzadeh is an academic researcher from University of Tabriz. The author has contributed to research in topics: Homeobox protein NANOG & SOX2. The author has an hindex of 3, co-authored 4 publications receiving 39 citations. Previous affiliations of Basira Najafzadeh include Tabriz University of Medical Sciences.

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The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV.

TL;DR: In this paper, the authors summarize alterations of cellular signaling pathways that are associated with coronavirus infection, particularly SARS-CoV and MERSCoV, and tabulate the therapeutic agents that are currently approved for treating other human diseases.
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Nanog, as a key cancer stem cell marker in tumor progression.

TL;DR: In this paper , a review aimed to focus on the function of Nanog in multiple cancers based on recent studies surveying the suitable approaches to target Nanog and inhibit CSCs residing in tumors to gain favorable results from cancer treatments.
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Signaling pathways and microRNAs, the orchestrators of NANOG activity during cancer induction.

TL;DR: This review will investigate the function of NANOG in CSCs and the molecular mechanism of its regulation by signaling pathways and miRNAs, which is a promising treatment strategy for cancer treatment.
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Silencing of Nanog as a promising therapeutic approach against liver cancer; how this silencing could increase the sensitivity to Cisplatin.

TL;DR: In this paper , the authors evaluated the impact of combination therapy of Nanog siRNA/cisplatin on the sensitivity of liver cancer cells to this drug and found that Nanog inhibition in combination with cisplatin is a potential therapeutic strategy for developing new therapeutic approaches for liver cancer.