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Bastiaan E. de Galan
Researcher at Maastricht University
Publications - 107
Citations - 8886
Bastiaan E. de Galan is an academic researcher from Maastricht University. The author has contributed to research in topics: Diabetes mellitus & Medicine. The author has an hindex of 20, co-authored 67 publications receiving 7942 citations. Previous affiliations of Bastiaan E. de Galan include Radboud University Nijmegen Medical Centre & Royal Prince Alfred Hospital.
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Journal ArticleDOI
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
Evita C Wiegers,Hanne M. M. Rooijackers,Cees J. Tack,Arend Heerschap,Bastiaan E. de Galan,Marinette van der Graaf +5 more
TL;DR: Brain lactate fell significantly by ∼20% in response to hypoglycemia in patients with type 1 diabetes with IAH but remained stable in both healthy control subjects and in patientswith NAH, which may contribute to the impaired detection of hypoglyCEmia.
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Needle-Free Jet Injection of Rapid-Acting Insulin Improves Early Postprandial Glucose Control in Patients With Diabetes
TL;DR: The considerably more rapid insulin absorption after administration by jet injector translated to a significant if modest decrease in postprandial hyperglycemia in patients with type 1 and type 2 diabetes, and may specifically benefit patients who have difficulty in limiting postPRandial glucose excursions.
Journal ArticleDOI
Patients with type 1 diabetes exhibit altered cerebral metabolism during hypoglycemia
Kim C.C. van de Ven,Cees J. Tack,Arend Heerschap,Marinette van der Graaf,Bastiaan E. de Galan +4 more
TL;DR: The data suggest that the brains of patients with T1DM are better able to endure moderate hypoglycemia than those of subjects without diabetes.
Journal ArticleDOI
A Single Bout of High-Intensity Interval Training Reduces Awareness of Subsequent Hypoglycemia in Patients With Type 1 Diabetes.
Hanne M. M. Rooijackers,Evita C Wiegers,Marinette van der Graaf,Dick H. J. Thijssen,Dick H. J. Thijssen,Roy P. C. Kessels,Cees J. Tack,Bastiaan E. de Galan +7 more
TL;DR: It is demonstrated that a single HIIT session rapidly reduces awareness of subsequent hypoglycemia in patients with type 1 diabetes and NAH, but does not in patientswith IAH, and attenuates hypoglyCEmia-induced cognitive dysfunction.
Journal ArticleDOI
Effect of Acute Hypoglycemia on Human Cerebral Glucose Metabolism Measured by 13C Magnetic Resonance Spectroscopy
Kim C.C. van de Ven,Bastiaan E. de Galan,Marinette van der Graaf,Alexander A. Shestov,Pierre-Gilles Henry,Cees J. Tack,Arend Heerschap +6 more
TL;DR: The results indicate that acute moderate hypoglycemia does not affect fluxes through the main pathways of glucose metabolism in the brain of healthy nondiabetic subjects.