B
Bastiaan E. de Galan
Researcher at Maastricht University
Publications - 107
Citations - 8886
Bastiaan E. de Galan is an academic researcher from Maastricht University. The author has contributed to research in topics: Diabetes mellitus & Medicine. The author has an hindex of 20, co-authored 67 publications receiving 7942 citations. Previous affiliations of Bastiaan E. de Galan include Radboud University Nijmegen Medical Centre & Royal Prince Alfred Hospital.
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Journal ArticleDOI
Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type 2 diabetes: a prospective cohort study from ADVANCE
Sébastien Czernichow,Sébastien Czernichow,Andre Pascal Kengne,Rachel R. Huxley,G. D. Batty,G. D. Batty,Bastiaan E. de Galan,Diederick E. Grobbee,Avinesh Pillai,Sophia Zoungas,Sophia Zoungas,Michel Marre,Mark Woodward,Bruce Neal,John Chalmers +14 more
TL;DR: Strengths of associations and discrimination statistics suggested that WHR was the best predictor of cardiovascular events and mortality in patients with type-2 diabetes and BMI the worst.
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Improved Pharmacokinetic and Pharmacodynamic Profile of Rapid-Acting Insulin Using Needle-Free Jet Injection Technology
TL;DR: Administration of insulin aspart by jet injection enhances insulin absorption and reduces the duration of glucose-lowering action and may help to achieve better meal insulin coverage and correction of postprandial glucose excursions.
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Erectile Dysfunction and Later Cardiovascular Disease in Men With Type 2 Diabetes Prospective Cohort Study Based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) Trial
G. David Batty,G. David Batty,G. David Batty,Qiang Li,Sébastien Czernichow,Sébastien Czernichow,Bruce Neal,Sophia Zoungas,Rachel R. Huxley,Anushka Patel,Bastiaan E. de Galan,Bastiaan E. de Galan,Mark Woodward,Pavel Hamet,Stephen B. Harrap,Neil R Poulter,John Chalmers +16 more
TL;DR: In this cohort of men with type 2 diabetes, ED was associated with a range of CVD events, and men who experienced ED at baseline and at 2-year follow-up had the highest risk for these outcomes.
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In vitro and in vivo Effects of Lactate on Metabolism and Cytokine Production of Human Primary PBMCs and Monocytes.
Jacqueline M. Ratter,Jacqueline M. Ratter,Hanne M. M. Rooijackers,Guido J. E. J. Hooiveld,Anneke Hijmans,Bastiaan E. de Galan,Cees J. Tack,Rinke Stienstra,Rinke Stienstra +8 more
TL;DR: Interestingly, long-term treatment with lactate ex vivo, reflecting pathophysiological conditions in local microenvironments such as tumor or adipose tissue, significantly modulated cytokine production with predominantly anti-inflammatory effects.
Journal ArticleDOI
Proinflammatory Effects of Hypoglycemia in Humans With or Without Diabetes
Jacqueline M. Ratter,Jacqueline M. Ratter,Hanne M. M. Rooijackers,Cees J. Tack,Anneke Hijmans,Mihai G. Netea,Bastiaan E. de Galan,Rinke Stienstra,Rinke Stienstra +8 more
TL;DR: Ex vivo ex vivo stimulations of peripheral blood mononuclear cells and monocytes obtained during hyperinsulinemic-euglycemic-hypoglycemic clamps concluded that hypoglycemia promotes mobilization of specific leukocyte subsets from the marginal pool and induces proinflammatory functional changes in immune cells.