B
Bengt Sandstedt
Researcher at Karolinska Institutet
Publications - 102
Citations - 5037
Bengt Sandstedt is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Wilms' tumor & Neuroblastoma. The author has an hindex of 42, co-authored 101 publications receiving 4577 citations. Previous affiliations of Bengt Sandstedt include Boston Children's Hospital.
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Journal ArticleDOI
Revised International Society of Paediatric Oncology (SIOP) working classification of renal tumors of childhood.
TL;DR: The results of the latest International Society of Paediatric Oncology (SIOP) trials and studies showed that certain histological features which remain after preoperative chemotherapy, such as blastema, are of prognostic significance while others are not as discussed by the authors.
Journal ArticleDOI
Optimal Duration of Preoperative Therapy in Unilateral and Nonmetastatic Wilms’ Tumor in Children Older Than 6 Months: Results of the Ninth International Society of Pediatric Oncology Wilms’ Tumor Trial and Study
Marie-France Tournade,C Com-Nougué,J. de Kraker,R. Ludwig,Annie Rey,J. M.B. Burgers,Bengt Sandstedt,J. Godzinski,Modesto Carli,R. Potter,Jean-Michel Zucker +10 more
TL;DR: The 4-week schedule pre-nephrectomy chemotherapy regimen should be considered the standard treatment and should continue to improve the cure rate of high-risk patients and the quality of life of children with a more favorable prognosis.
Journal ArticleDOI
Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta.
Ulrika Holmlund,Gvido Cebers,Agneta R. Dahlfors,Bengt Sandstedt,Katarina Bremme,Eva S. EkstrÖm,Annika Scheynius +6 more
TL;DR: A novel mechanism for the fetoplacental unit to interact with micro‐organisms is suggested, which shows a strong immunoreactivity for TLR2 and TLR4 in the villous and the intermediate trophoblasts.
Journal ArticleDOI
Effectiveness of preoperative chemotherapy in Wilms' tumor: results of an International Society of Paediatric Oncology (SIOP) clinical trial.
Jean Lemerle,P.A. Voûte,Marie-France Tournade,C Rodary,J. F. M. Delemarre,D Sarrazin,J. M. V. Burgers,Bengt Sandstedt,H Mildenberger,Modesto Carli +9 more
TL;DR: Preoperative chemotherapy is as good as preoperative radiotherapy in terms of prevention of tumor rupture, and 43% of an unselected population of patients with Wilms' tumor could be treated without any radiotherapy when chemotherapy had been given preoperatively.
Journal ArticleDOI
Reduction of postoperative chemotherapy in children with stage I intermediate-risk and anaplastic Wilms' tumour (SIOP 93-01 trial): a randomised controlled trial.
J. de Kraker,Norbert Graf,H. van Tinteren,F. Pein,Bengt Sandstedt,J. Godzinski,Marie-France Tournade +6 more
TL;DR: Whether postoperative chemotherapy for patients with stage I intermediate-risk and anaplastic Wilms' tumour could be shortened to only 4 weeks from the standard 18 weeks, while maintaining equivalent event-free survival is assessed.