P
P.A. Voûte
Researcher at University of Amsterdam
Publications - 73
Citations - 4883
P.A. Voûte is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Wilms' tumor & Rhabdomyosarcoma. The author has an hindex of 33, co-authored 73 publications receiving 4747 citations. Previous affiliations of P.A. Voûte include VU University Amsterdam.
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Journal ArticleDOI
The Human Transcriptome Map: Clustering of Highly Expressed Genes in Chromosomal Domains
Huib N. Caron,Barbera D. C. van Schaik,Merlijn van der Mee,Frank Baas,Gregory J. Riggins,Peter van Sluis,Marie-Christine Hermus,Ronald van Asperen,Kathy Boon,P.A. Voûte,S. H. Heisterkamp,Antoine H. C. van Kampen,Rogier Versteeg +12 more
TL;DR: The Human Transcriptome Map (HPM) as mentioned in this paper is a tool to search for genes that are overexpressed or silenced in cancer using the SAGE serial analysis of gene expression.
Journal ArticleDOI
Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma.
H.N. Caron,P. van Sluis,J. de Kraker,Jos P.M. Bökkerink,M Egeler,Genevieve Laureys,Rosalyn Slater,Andries Westerveld,P.A. Voûte,Rogier Versteeg +9 more
TL;DR: The loss of chromosome 1p is a strong prognostic factor in patients with neuroblastoma, independently of age and stage, and reliably identifies patients at high risk in stages I, II, and IVS, which are otherwise clinically favorable.
Journal ArticleDOI
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis.
Kathy Boon,Kathy Boon,Huib N. Caron,Ronald van Asperen,Linda J. Valentijn,Marie Christine Hermus,Peter van Sluis,Ilja Roobeek,Isabel Weis,P.A. Voûte,Manfred Schwab,Rogier Versteeg +11 more
TL;DR: In this paper, the authors applied serial analysis of gene expression (SAGE) to identify targets of N-myc in neuroblastoma cells and found that the large majority of the ribosomal proteins were induced, as well as genes controlling rRNA maturation.
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A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup.
Vivien H.C. Bramwell,M Burgers,R Sneath,Robert L. Souhami,A. van Oosterom,P.A. Voûte,Jacques Rouëssé,D. Spooner,Alan W. Craft,Riet Somers +9 more
TL;DR: A brief intensive chemotherapy regimen of DOX/CDDP has produced excellent long-term results, which are similar to those that have been achieved in cooperative group studies of longer, more complex multiagent chemotherapy, and provide the basis for a direct comparison in the next EOI study.
Journal ArticleDOI
Effectiveness of preoperative chemotherapy in Wilms' tumor: results of an International Society of Paediatric Oncology (SIOP) clinical trial.
Jean Lemerle,P.A. Voûte,Marie-France Tournade,C Rodary,J. F. M. Delemarre,D Sarrazin,J. M. V. Burgers,Bengt Sandstedt,H Mildenberger,Modesto Carli +9 more
TL;DR: Preoperative chemotherapy is as good as preoperative radiotherapy in terms of prevention of tumor rupture, and 43% of an unselected population of patients with Wilms' tumor could be treated without any radiotherapy when chemotherapy had been given preoperatively.