Benício de Barros Neto

TL;DR: The surface response methodologies: central composite design, Doehlert matrix and Box-Behnken design are discussed and applications of these techniques for optimization of sample preparation steps and determination of experimental conditions for chromatographic separations are presented.

TL;DR: A review of the use of the Doehlert matrix as a chemometric tool for the optimization of methods in analytical chemistry and other sciences is presented and 57 references concerning the application of DoehLert matrices in the optimized procedures involving spectroanalytical, electroanalytical and chromatographic techniques are considered.

TL;DR: In this article, the authors used an aqueous two-phase system of PEG/citrate to remove proteases from a Clostridium perfringens fermentation broth.

TL;DR: QUE/RES-loaded elastic liposomes are stable and suitable for subcutaneous injection, thereby providing a new strategy for reducing sub cutaneous fat.

TL;DR: OCT images support the idea that chitosan may act as a barrier against acid penetration, contributing to its demineralization inhibition, and microhardness measurements may be used as an indication of mineral loss from tooth enamel.