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Benjamin C. Moeller
Researcher at University of California, Davis
Publications - 49
Citations - 1886
Benjamin C. Moeller is an academic researcher from University of California, Davis. The author has contributed to research in topics: DNA damage & Pharmacokinetics. The author has an hindex of 21, co-authored 46 publications receiving 1535 citations. Previous affiliations of Benjamin C. Moeller include Lovelace Respiratory Research Institute & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Endogenous versus Exogenous DNA Adducts: Their Role in Carcinogenesis, Epidemiology, and Risk Assessment
James A. Swenberg,Kun Lu,Benjamin C. Moeller,Lina Gao,Patricia B. Upton,Jun Nakamura,Thomas B. Starr +6 more
TL;DR: 30 years of research on three "known human carcinogens": formaldehyde, vinyl chloride (VC), and ethylene oxide (EO) are utilizes, which outlines quantitative data on endogenous adducts, mutagenicity, and relationships between endogenous and exogenousAdducts.
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Simvastatin Reduces Steroidogenesis by Inhibiting Cyp17a1 Gene Expression in Rat Ovarian Theca-Interstitial Cells
Israel Ortega,Amanda B. Cress,Donna H. Wong,Jesus A. Villanueva,Anna Sokalska,Benjamin C. Moeller,Scott D Stanley,Antoni J. Duleba +7 more
TL;DR: The present findings indicate that statin-induced reduction of androgen levels is likely due, at least in part, to the inhibition of isoprenylation, resulting in decreased expression of CYP17A1.
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Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment.
TL;DR: The complexity of constant physiologic exposure to a known carcinogen requires that new ways of thinking be incorporated into determinations of cancer risk assessment for formaldehyde, other endogenous carcinogens, and the role of background endogenous DNA damage and mutagenesis.
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Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis
Yohannes T. Ghebremariam,Yohannes T. Ghebremariam,John P. Cooke,William Gerhart,Carol Griego,Jeremy Brower,Melanie Doyle-Eisele,Benjamin C. Moeller,Qingtao Zhou,Lawrence A. Ho,Joao A. de Andrade,Ganesh Raghu,Leif E. Peterson,Andreana L. Rivera,Glenn D. Rosen +14 more
TL;DR: The data indicate the possibility that PPIs may have protective function in IPF by directly modulating the disease process and suggest that they may have other clinical utility in the treatment of extra-intestinal diseases characterized by inflammatory and/or fibrotic phases.
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Molecular dosimetry of N2-hydroxymethyl-dG DNA adducts in rats exposed to formaldehyde.
TL;DR: The data clearly demonstrated that exogenous formaldehyde DNA adducts form in a highly nonlinear fashion, with a 21.7-fold increase in exposure causing a 286- fold increase in exogenous adduction.