Berislav Lisnić

TL;DR: A dual analysis of Murine Cytomegalovirus and host cell transcriptomes during lytic infection and numerous novel spliced and unspliced transcripts of MCMV is conducted, finding that the most abundant viral transcript, recently identified as a noncoding RNA regulating cellular microRNAs, also codes for a novel protein.

TL;DR: Understanding these processes will allow us to design better diagnostic approaches and new treatment options through manipulation of the authors' immune responses and the viruses themselves.

TL;DR: This unit describes procedures for infecting newborn and adult mice with murine cytomegalovirus (MCMV), and methods for propagating MCMV in cell cultures and for preparing a more virulent form of MCMVs from salivary glands of infected mice.

TL;DR: A computer program is developed that can identify, locate and count palindromes in a given sequence in a strictly defined way and indicates a strong bias against palINDromic dinucleotides that could explain the observed short palindrome avoidance.

TL;DR: The activating receptor NKG2D specifically sets the activation threshold for the activating receptor NCR1 through a process that required the adaptor DAP12, providing a mechanism distinct from previously known mechanisms of NK cell education.