C
Charles H. Cook
Researcher at Beth Israel Deaconess Medical Center
Publications - 166
Citations - 5210
Charles H. Cook is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Intensive care unit & Congenital cytomegalovirus infection. The author has an hindex of 38, co-authored 165 publications receiving 4531 citations. Previous affiliations of Charles H. Cook include Brigham and Women's Hospital & Ohio State University.
Papers
More filters
Journal ArticleDOI
Trial of Short-Course Antimicrobial Therapy for Intraabdominal Infection
Robert G. Sawyer,Jeffrey A. Claridge,Avery B. Nathens,Ori D. Rotstein,Therese M. Duane,Heather L. Evans,Charles H. Cook,Patrick J. O'Neill,John E. Mazuski,Reza Askari,Mark A. Wilson,Lena M. Napolitano,Nicholas Namias,Preston R. Miller,E. Patchen Dellinger,Christopher M. Watson,Raul Coimbra,Daniel L. Dent,Stephen F. Lowry,Christine S. Cocanour,Michael West,Kaysie L. Banton,William G. Cheadle,Pamela A. Lipsett,Christopher A. Guidry,Kimberley A. Popovsky +25 more
TL;DR: In patients with intraabdominal infections who had undergone an adequate source-control procedure, the outcomes after fixed-duration antibiotic therapy were similar to those after a longer course of antibiotics that extended until after the resolution of physiological abnormalities.
Journal ArticleDOI
Mixed-species biofilm compromises wound healing by disrupting epidermal barrier function.
Sashwati Roy,Haytham Elgharably,Mithun Sinha,Kasturi Ganesh,Sarah B. Chaney,Ethan E. Mann,Christina Miller,Savita Khanna,Valerie K. Bergdall,Heather M. Powell,Charles H. Cook,Gayle M. Gordillo,Daniel J. Wozniak,Chandan K. Sen +13 more
TL;DR: This work establishes the first chronic preclinical model of wound biofilm infection aimed at addressing the long‐term host response and leads to the notion that even if a biofilm infected wound is closed, it may be complicated by the presence of failed skin, which is likely to be infected and/or further complicated postclosure.
Journal ArticleDOI
Pain and wound healing in surgical patients.
Lynanne McGuire,Kathi L. Heffner,Ronald Glaser,Bradley Needleman,William B. Malarkey,Stephanie L. Dickinson,Stanley Lemeshow,Charles H. Cook,Peter Muscarella,W.S. Melvin,E. C. Ellison,Janice K. Kiecolt-Glaser +11 more
TL;DR: These findings extend the previous laboratory models of wound healing to a surgical population, providing the first evidence that pain plays an important role in postsurgery wound healing, a key variable in postsurgical recovery.
Journal ArticleDOI
Complications associated with pulmonary artery catheters: a comprehensive clinical review.
David C. Evans,Vijay A. Doraiswamy,M. P. Prosciak,Matthew L. Silviera,Mark J. Seamon,V. Rodriguez Funes,James Cipolla,Cecilia F. Wang,Srinivas Kavuturu,Drew A. Torigian,Charles H. Cook,David E. Lindsey,Steven M. Steinberg,Stanislaw P Stawicki +13 more
TL;DR: This review categorizes complications associated with the Pulmonary artery catheters into four broad groups — Complications of central venous access; complications related to PAC insertion and manipulation; complicationsassociated with short- or long-term presence of the PAC in the cardiovascular system; and errors resulting from incorrect interpretation/use of PAC-derived data.
Journal ArticleDOI
Designing isoform-specific peptide disruptors of protein kinase A localization
Lora L. Burns-Hamuro,Yuliang Ma,Stefan Kammerer,Ulrich Reineke,Christopher Self,Charles H. Cook,Gary L. Olson,Charles R. Cantor,Andreas Braun,Susan S. Taylor +9 more
TL;DR: To evaluate the effects of each localized isoform, peptides that specifically bind to either RI or RII are designed that will be invaluable tools to evaluate functional differences between localized RI and RII PKA and are RIα-specific disruptors.