R
Roy E. Smith
Researcher at University of Pittsburgh
Publications - 78
Citations - 9751
Roy E. Smith is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Chemotherapy & Breast cancer. The author has an hindex of 26, co-authored 75 publications receiving 9249 citations. Previous affiliations of Roy E. Smith include Allegheny University of the Health Sciences & Medical College of Wisconsin.
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Journal ArticleDOI
Reduction by Granulocyte Colony-Stimulating Factor of Fever and Neutropenia Induced by Chemotherapy in Patients with Small-Cell Lung Cancer
Jeffrey Crawford,Howard Ozer,Ronald G. Stoller,David H. Johnson,Gary H. Lyman,Imad A. Tabbara,Mark G. Kris,John Grous,Vincent J. Picozzi,Gregory Rausch,Roy E. Smith,William J. Gradishar,Anne M. Yahanda,Martha Vincent,Morgan Stewart,John A. Glaspy +15 more
TL;DR: A randomized clinical trial to test the hypothesis that recombinant methionyl granulocyte colony-stimulating factor (G-CSF) can reduce chemotherapy-related neutropenia in patients with cancer and the clinical implications.
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The Effect on Tumor Response of Adding Sequential Preoperative Docetaxel to Preoperative Doxorubicin and Cyclophosphamide: Preliminary Results From National Surgical Adjuvant Breast and Bowel Project Protocol B-27
Harry D. Bear,Stewart J. Anderson,Ann M. Brown,Roy E. Smith,Eleftherios P. Mamounas,Bernard Fisher,Richard G. Margolese,Heather Theoret,Atilla Soran,D. Lawrence Wickerham,Norman Wolmark +10 more
TL;DR: The addition of four cycles of preoperative docetaxel after four cyclesof preoperative AC significantly increased clinical and pathologic response rates for operable breast cancer.
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Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial
B Fisher,James J. Dignam,Norman Wolmark,D. Lawrence Wickerham,Edwin R. Fisher,Eleftherios P. Mamounas,Roy E. Smith,Mirsada Begovic,Nikolay V. Dimitrov,Richard G. Margolese,Carl G Kardinal,Maureen T. Kavanah,Louis Fehrenbacher,Robert H Oishi +13 more
TL;DR: The combination of lumpectomy, radiation therapy, and tamoxifen was effective in the prevention of invasive cancer and the risk of ipsilateral-breast cancer was lower in the tamoxIFen group even when sample margins contained tumour and when DCIS was associated with comedonecrosis.
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Oxaliplatin Combined With Weekly Bolus Fluorouracil and Leucovorin As Surgical Adjuvant Chemotherapy for Stage II and III Colon Cancer: Results From NSABP C-07
J. Philip Kuebler,H. Samuel Wieand,Michael O’Connell,Roy E. Smith,Linda H. Colangelo,Greg Yothers,N. J. Petrelli,Michael Findlay,Thomas E. Seay,James N. Atkins,John L. Zapas,J. Wendall Goodwin,Louis Fehrenbacher,Ramesh K. Ramanathan,Barbara A. Conley,Patrick J. Flynn,Gamini S. Soori,Lauren K. Colman,Edward A. Levine,Keith S. Lanier,Norman Wolmark +20 more
TL;DR: The addition of oxaliplatin to weekly FULV significantly improved DFS in patients with stage II and III colon cancer, and FLOX can be recommended as an effective option in clinical practice.
Journal ArticleDOI
Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer : National surgical adjuvant breast and bowel project protocol B-27
Harry Douglas Bear,Stewart J. Anderson,Roy E. Smith,Charles E. Geyer,Eleftherios P. Mamounas,Bernard Fisher,Ann M. Brown,André Robidoux,Richard G. Margolese,Morton S. Kahlenberg,Soonmyung Paik,Atilla Soran,D. Lawrence Wickerham,Norman Wolmark +13 more
TL;DR: The addition of preoperative or postoperative T after preoperative AC did not significantly affect OS, slightly improved DFS, and decreased the incidence of local recurrences.