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Bernard Pirotte

Researcher at University of Liège

Publications -  269
Citations -  4745

Bernard Pirotte is an academic researcher from University of Liège. The author has contributed to research in topics: Benzothiadiazine & Diazoxide. The author has an hindex of 37, co-authored 262 publications receiving 4249 citations. Previous affiliations of Bernard Pirotte include Université libre de Bruxelles & Centre national de la recherche scientifique.

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New Trends in Dual 5-LOX / COX Inhibition

Xavier de Leval, +4 more
- 01 May 2002 - 
TL;DR: Both COX and LOX derivatives (prostanoids and leukotrienes, respectively) are involved in other diseases than inflammation such as cancer proliferation where the use of dual inhibitors could be an interesting approach.
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3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo.

I. Kempen, +9 more
- 07 Apr 2003 - 
TL;DR: These two coumarin derivatives may serve as new lead compounds of an original class of antitumour agents and are evaluated for antiinvasive and antimigrative properties among which two compounds revealed important activity.
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Study of the Influence of Both Cyclodextrins and L-Lysine on the Aqueous Solubility of Nimesulide; Isolation and Characterization of Nimesulide–L-Lysine–Cyclodextrin Complexes

Géraldine Piel, +6 more
- 01 Apr 1997 - 
TL;DR: The purpose of the present study was to investigate the interaction of both cyclodextrins and L-lysine on the aqueous solubility of nimesulide.
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Insight into SUCNR1 (GPR91) structure and function.

Julie Gilissen, +3 more
- 01 Mar 2016 - 
TL;DR: SUCNR1 shows a high potential as an innovative drug target and is probably an important regulator of basic physiology and more specific pharmacological tools such as small-molecules modulators will represent an important asset in order to achieve the full characterization of this receptor.
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New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators.

Jean-Michel Dogné, +10 more
- 01 May 2004 - 
TL;DR: This review will propose a description of the recently described thromboxane modulators of major interest, which combine another pharmacological activity such as, platelet activating factor antagonism, angiotensin II antagonism or 5-lipoxygenase inhibition.