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JournalISSN: 0163-7258

Pharmacology & Therapeutics 

Elsevier BV
About: Pharmacology & Therapeutics is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Receptor. It has an ISSN identifier of 0163-7258. Over the lifetime, 4151 publications have been published receiving 379619 citations. The journal is also known as: Therapeutics.

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Journal ArticleDOI
TL;DR: Recent progress on drug metabolism activity profiles, interindividual variability and regulation of expression, and the functional and clinical impact of genetic variation in drug metabolizing P450s are reviewed.

2,832 citations

Journal ArticleDOI
TL;DR: Flavonoids are plant pigments that are synthesised from phenylalanine, generally display marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are excited by UV light, and are ubiquitous to green plant cells.

2,424 citations

Journal ArticleDOI
TL;DR: This review summarizes the current knowledge of the most important GC-mediated side effects from a clinical to a molecular perspective and should be helpful in predicting the potential advantages of selective GR agonists in comparison to classical GCs.

1,624 citations

Journal ArticleDOI
TL;DR: The biology of T NF and related family members are discussed in the context of the potential mechanisms of action of TNF antagonists in a variety of immune-mediated inflammatory diseases.

1,517 citations

Journal ArticleDOI
TL;DR: This review focuses on the classification, binding properties, effector systems and distribution of cannabinoid receptors, and describes the various cannabinoid receptor agonists and antagonists now available and considers the main in vivo and in vitro bioassay methods that are generally used.

1,456 citations

No. of papers from the Journal in previous years