Bernd Sido

TL;DR: Investigation of constituent amino acid plasma levels and the GSH redox status in different compartments in IBD with emphasis on intestinal GSH synthesis in Crohn’s disease found reduced rGSH levels and increased GSSG levels were demonstrated in non-inflamed mucosa in patients with IBD.

TL;DR: Considering that the 5‐year survival rate in patients with neuro endocrine carcinomas of the ampulla of Vater is very low without radical resection, neuroendocrine tumors of theampullary carcinoids without definite histological differentiation should undergo extended surgery.

TL;DR: Laroscopic surgery decreases the local and systemic production of cytokines and acute-phase reactants, and better preserves peritoneal immunity compared with open surgery, as concluded from animal studies, the gas used for the pneumoperitoneum may possess substantial immunomodulatory activity.

TL;DR: In histologically noninflamed/inactive IBD samples mRNAs for several mediators were significantly enhanced, accompanied by elevated levels of migration-inhibition factor related protein (MRP) 14 transcripts, indicating a substantial overlap in cytokine/chemokine mRNA expression in UC and CD.

TL;DR: CD28 antibody JJ319 induces profound immunosuppression after rat heart transplantation, however without development of transplant tolerance, and the underlying mechanism seems to be receptor modulation during primary alloantigen recognition.