Mark Hartel

TL;DR: In pancreatic adenocarcinoma, the VEGF expression and the height of MVD are closely correlated, and both—rather than UICC stage and TNM classification—are markers of prognostic relevance after curative resection.

TL;DR: TFRC represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target in solid tumours expressing this antigen.

TL;DR: In this paper, the authors quantified the mRNA expression of BCRP and all the members of the MRP family in normal human pancreas and pancreatic carcinoma and analyzed the mRNA level of the transporters most abundantly expressed in pancreatic tissue, including MRP, MDR1 P-glycoprotein (ABCB1), MRP3, MRP4 and MRP5, in 37 tissue samples.

TL;DR: Resection of the superior mesenteric or portal vein to achieve macroscopic tumor clearance can be performed safely with acceptable operative morbidity and mortality, however, improved local clearance in these patients cannot achieve a favorable long-term survival for all patients.

TL;DR: The results show that pancreatic resections for metastasis can be performed safely with a low rate of complications, and patients with a history of RCC should undergo a long-term follow-up to detect and evaluate for pancreatic metastases as well for metastases to other organ sites.