Berrak Ç. Yeğen

TL;DR: In gastric fistula rats, vagal afferent denervation and peripheral administration of the GLP-1 receptor antagonist exendin enhanced emptying of a glucose meal, whereas intracerebroventricularExendin was ineffective, and the notion that GLP1 receptors participate in the central and peripheral regulation of gastric function is supported.

TL;DR: The present study suggests that melatonin may be of therapeutic benefit when used with MTX and elucidates the role of free radicals in MTX‐induced toxicity and the protection by melatonin.

TL;DR: The findings of the present study suggest that beta-glucan, through its antioxidant and immunoregulatory effects, may be of therapeutic value in alleviating the leukocyte apoptosis, oxidative tissue injury and thereby the intestinal and hepatorenal side effects of methotrexate treatment.

TL;DR: It appears that taurine protects against methotrexate-induced oxidant organ injury and inhibits leukocyte apoptosis and may be of therapeutic potential in alleviating the systemic side effects of chemotherapeutics.

TL;DR: RVT markedly ameliorated the severity of cardiac dysfunction, while all oxidant responses were prevented, implicating that RVT may be of therapeutic use in preventing oxidative stress due to DOX toxicity.