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Bert L. Vallee
Researcher at Brigham and Women's Hospital
Publications - 18
Citations - 2597
Bert L. Vallee is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Zinc & Binding site. The author has an hindex of 13, co-authored 18 publications receiving 2518 citations.
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Journal ArticleDOI
Zinc coordination, function, and structure of zinc enzymes and other proteins
Bert L. Vallee,David S. Auld +1 more
Journal ArticleDOI
Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains
TL;DR: In this paper, three distinct motifs of DNA-binding zinc proteins are recognized: zinc fingers, zinc clusters, and zinc twists, and the structural and functional significance of these motifs in their binding to DNA and other proteins participating in the transmission of the genetic message will become apparent.
Journal ArticleDOI
New perspective on zinc biochemistry: cocatalytic sites in multi-zinc enzymes.
Bert L. Vallee,David S. Auld +1 more
Journal ArticleDOI
New human liver alcohol dehydrogenase forms with unique kinetic characteristics
Xavier Parés,Bert L. Vallee +1 more
TL;DR: Although the physical characteristics of the new anodic ADH forms are similar to those of the known human ADH isoenzymes, the former are not inhibited by 12 mM 4-methyl pyrazole, oxidize ethanol very poorly and appear to prefer longer chain alcohols as substrates.
Journal ArticleDOI
Short and long spacer sequences and other structural features of zinc binding sites in zinc enzymes.
Bert L. Vallee,David S. Auld +1 more
TL;DR: Metalloenzyme; Metalloproteinase; Zinc; Amino acid spacer sequence; Aminosine; Aminophosphorus; zinc; Metalloenzyme ; Metallop Proteinase ; and Zinc.