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Beth A. Pangallo

Researcher at Eli Lilly and Company

Publications -  18
Citations -  749

Beth A. Pangallo is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Duloxetine & Placebo. The author has an hindex of 12, co-authored 18 publications receiving 625 citations.

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Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial

Désirée van der Heijde, +90 more
- 08 Dec 2018 - 
TL;DR: Each dosing regimen of ixekizumab was superior to placebo for improving radiographic axial spondyloarthritis signs and symptoms in patients not previously treated with bDMARDs; the safety profile was consistent with previous indications of IXekzumab.
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Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine.

TL;DR: The cardiovascular effects of duloxetine appear to be comparable with medications considered to be first-line options for depression, and no clinically meaningful effect on electrocardiogram profiles in a relatively healthy cohort of clinical trial patients.
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A double-blind efficacy and safety study of duloxetine fixed doses in children and adolescents with major depressive disorder.

TL;DR: Trial results were inconclusive, as neither the investigational drug (duloxetine) nor the active control (fluoxettine) separated from placebo on the CDRS-R at 10 weeks.
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A randomized, placebo-controlled study of duloxetine for the treatment of children and adolescents with generalized anxiety disorder

TL;DR: Duloxetine was superior to placebo on the primary efficacy analysis of mean change from baseline to week 10 on the PARS severity for GAD score, and safety results were consistent with the known safety profile of duloxETine in pediatric and adult patients.
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Effects of the Antidepressant Duloxetine on Body Weight: Analyses of 10 Clinical Studies

TL;DR: In this paper, the effect of duloxetine, an inhibitor of serotonin and norepinephrine reup-take, on body weight of patients with major depressive disorder (MDD) was assessed.