B
Betsy Layton
Researcher at University of Texas Southwestern Medical Center
Publications - 1
Citations - 7553
Betsy Layton is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: TLR4 & Toll-like receptor. The author has an hindex of 1, co-authored 1 publications receiving 7311 citations.
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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
Alexander Poltorak,Xiaolong He,Irina Smirnova,Mu Ya Liu,Christophe Van Huffel,Xin Du,Dale Birdwell,E. Alejos,M. Silva,Chris Galanos,Marina Freudenberg,Paola Ricciardi-Castagnoli,Betsy Layton,Bruce Beutler +13 more
TL;DR: The mammalian Tlr4 protein has been adapted primarily to subserve the recognition of LPS and presumably transduces the LPS signal across the plasma membrane.