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Betül Arica Yegin

Researcher at Hacettepe University

Publications -  7
Citations -  143

Betül Arica Yegin is an academic researcher from Hacettepe University. The author has contributed to research in topics: Tracheal Stenosis & Drug carrier. The author has an hindex of 4, co-authored 7 publications receiving 132 citations.

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Paclitaxel-Loaded Lipid Nanoparticles Prepared by Solvent Injection or Ultrasound Emulsification

TL;DR: Lipid nanoparticles demonstrated their potential as a promising pharmaceutical formulation of paclitaxel as an injectable carrier system and entrapped in an amorphous state in the lipid matrix.
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Lipid nanocapsule size analysis by hydrodynamic chromatography and photon correlation spectroscopy.

TL;DR: HDR was found to be an excellent tool for the determination of size and average size distribution of lipid nanocapsules and was able to detect micelles as a byproduct of nanocapule preparation while in PCS the sample dilution turned micells undetectable.
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Preparation and in vitro evaluation of 5-fluorouracil-loaded PCL nanoparticles for colon cancer treatment.

TL;DR: Encouraging results obtained offer reasons for optimism regarding the future of 5-FU nanoparticles as a promising drug delivery system which could be further improved by including either enteric coating or encapsulating the nanoparticles onto microparticles to overcome unanticipated degradation.
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Sulindac loaded alginate beads for a mucoprotective and controlled drug release.

TL;DR: Alginate formulations exhibit promising properties of a controlled release form for sulindac; meanwhile they provide a distinct tissue protection in the stomach and duodenum and microscopic analyses of the mucosal damage demonstrated a significant mucoprotective effect of all bead formulation compared to the free drug.
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Effect of Locally Applied Transforming Growth Factor Beta3 on Wound Healing and Stenosis Development in Tracheal Surgery

TL;DR: This was the first experiment in the literature to use a transforming growth factor beta3 (TGF-β3)/chitosan combination and it is intended to change the formulation and perform this study again with a different TGF- β3/chitOSan preparation.