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Betül Arica Yegin
Researcher at Hacettepe University
Publications - 7
Citations - 143
Betül Arica Yegin is an academic researcher from Hacettepe University. The author has contributed to research in topics: Tracheal Stenosis & Drug carrier. The author has an hindex of 4, co-authored 7 publications receiving 132 citations.
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Journal ArticleDOI
Paclitaxel-Loaded Lipid Nanoparticles Prepared by Solvent Injection or Ultrasound Emulsification
TL;DR: Lipid nanoparticles demonstrated their potential as a promising pharmaceutical formulation of paclitaxel as an injectable carrier system and entrapped in an amorphous state in the lipid matrix.
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Lipid nanocapsule size analysis by hydrodynamic chromatography and photon correlation spectroscopy.
Betül Arica Yegin,Alf Lamprecht +1 more
TL;DR: HDR was found to be an excellent tool for the determination of size and average size distribution of lipid nanocapsules and was able to detect micelles as a byproduct of nanocapule preparation while in PCS the sample dilution turned micells undetectable.
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Preparation and in vitro evaluation of 5-fluorouracil-loaded PCL nanoparticles for colon cancer treatment.
TL;DR: Encouraging results obtained offer reasons for optimism regarding the future of 5-FU nanoparticles as a promising drug delivery system which could be further improved by including either enteric coating or encapsulating the nanoparticles onto microparticles to overcome unanticipated degradation.
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Sulindac loaded alginate beads for a mucoprotective and controlled drug release.
Betül Arica Yegin,Brice Moulari,N. Tugba Durlu-Kandilci,Petek Korkusuz,Yann Pellequer,Alf Lamprecht +5 more
TL;DR: Alginate formulations exhibit promising properties of a controlled release form for sulindac; meanwhile they provide a distinct tissue protection in the stomach and duodenum and microscopic analyses of the mucosal damage demonstrated a significant mucoprotective effect of all bead formulation compared to the free drug.
Journal ArticleDOI
Effect of Locally Applied Transforming Growth Factor Beta3 on Wound Healing and Stenosis Development in Tracheal Surgery
Aykut Eliçora,Serife Tuba Liman,Betül Arica Yegin,Asli Gül Akgül,Hakan Eroglu,Kürşat Yildiz,Salih Topçu,Cuneyt Ozer +7 more
TL;DR: This was the first experiment in the literature to use a transforming growth factor beta3 (TGF-β3)/chitosan combination and it is intended to change the formulation and perform this study again with a different TGF- β3/chitOSan preparation.