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Bilal Shaker
Researcher at Chung-Ang University
Publications - 13
Citations - 232
Bilal Shaker is an academic researcher from Chung-Ang University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 6 publications receiving 37 citations.
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In silico methods and tools for drug discovery.
TL;DR: A review of computational drug discovery strategies can be found in this article, where up-to-date tools to perform the strategies as well as available knowledge bases for those who develop their own computational models are discussed.
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LightBBB: computational prediction model of blood-brain-barrier penetration based on LightGBM.
TL;DR: A machine learning model based on Light Gradient Boosting Machine (LightGBM) algorithm that outperforms over existing BBB permeability prediction models and can be used for facilitated compound screening in the early stage of brain drug discovery.
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User guide for the discovery of potential drugs via protein structure prediction and ligand docking simulation
TL;DR: An in silico drug discovery protocol for multi-drug resistance of pathogenic bacteria, using UDP-N-acetylmuramate-L-alanine ligase of Acinetobacter baumannii as an example, is introduced to help microbiologists to expand their knowledge and research scope.
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Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii
Mir Jalal ud-din,Aqel Albutti,Asad Ullah,Saba Ismail,Sajjad Ahmad,Anam Naz,Muhammad Khurram,Mahboob Ul Haq,Zobia Afsheen,Youness El Bakri,Muhammad Salman,Bilal Shaker,Muhammad Tahir ul Qamar +12 more
TL;DR: The results suggested that the designed vaccine construct has high potential to induce protective host immune responses and can be a good vaccine candidate for experimental in vivo and in vitro studies.
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Rational Drug Design for Pseudomonas aeruginosa PqsA Enzyme: An in silico Guided Study to Block Biofilm Formation.
TL;DR: A rational drug design strategy is used to inhibit the quorum signaling system of P. aeruginosa by designing potent inhibitory lead molecules against anthranilate-CoA ligase enzyme encoded by the pqsA gene.