Binayak Kumar

TL;DR: Colorectal cancer gene database (CoReCG) is expected to be a single point source for identification of coloreCTal cancer-related genes, thereby helping with the improvement of classification, diagnosis and treatment of human cancers.

TL;DR: No significant change in the expression level of Cu-metabolism-related genes, including metallothioneines MT1A, is observed in liver cells co-treated with Cu and 1, as opposed to the large increase in the concentrations of these genes observed in cells treated with Cu alone, suggesting the participation of 1 in Cu homeostasis in hepatocyte.

TL;DR: ImMeSH (2) showed a promising effect in protecting the metal ion from H2O2-mediated oxidation and protected biomolecules from Cu(I)-mediated oxidative damage of through coordination to theCu(I) center of [TpmCu(CH3CN)]+ (11), whereas metal-bound ImMeSMe or BzMeS me failed to protect biomolecule under identical reaction conditions.

TL;DR: In this article , the synthesis, characterization, and X-ray structure of a series of mono, tri, and polynuclear copper complexes of benzimidazole-based N-substituted thiones, BzMeSH (10) and BzOHSH (11), and N,N-disubstitiuted, bzMeSMe (12) and bz OHSMe (13) are reported.

TL;DR: In this paper , the authors summarized the most recent progress in stimuli-based dual drug-delivery systems including inorganic and organic nanocarriers, and highlighted the specific stimuli responsive nano-MOFs as dual drug delivery systems, which offer a fresh perspective for development of hybrid nanoccarrier to overcome the drawbacks of pure organic and inorganic carriers, such as toxicity, lower payload capacity and burst effect.