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Bing Chen
Researcher at Fudan University
Publications - 11
Citations - 2405
Bing Chen is an academic researcher from Fudan University. The author has contributed to research in topics: RNA & Circular RNA. The author has an hindex of 7, co-authored 8 publications receiving 1719 citations.
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Journal ArticleDOI
Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs
Qiupeng Zheng,Chunyang Bao,Weijie Guo,Weijie Guo,Shuyi Li,Shuyi Li,Jie Chen,Bing Chen,Yanting Luo,Dongbin Lyu,Yan Li,Guohai Shi,Linhui Liang,Jianren Gu,Xianghuo He,Shenglin Huang +15 more
TL;DR: The results provide evidence that circular RNA produced from precursor mRNA may have a regulatory role in human cells and characterize one abundant circRNA derived from Exon2 of the HIPK3 gene, termed circHIPK3.
Journal ArticleDOI
exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes.
Shengli Li,Yuchen Li,Bing Chen,Jingjing Zhao,Shulin Yu,Yan Tang,Qiupeng Zheng,Yan Li,Peng Wang,Xianghuo He,Shenglin Huang +10 more
TL;DR: ExoRBase will aid researchers in identifying molecular signatures in blood exosomes and will trigger new exosomal biomarker discovery and functional implication for human diseases.
Journal ArticleDOI
Circular RNA: An emerging non-coding RNA as a regulator and biomarker in cancer.
Bing Chen,Shenglin Huang +1 more
TL;DR: The current knowledge of circRNAs is summarized, including their classification, biogenesis, properties, and databases, as well as their function and clinical implications in cancer.
Journal ArticleDOI
MetaLnc9 Facilitates Lung Cancer Metastasis via a PGK1-Activated AKT/mTOR Pathway.
Tao Yu,Yingjun Zhao,Zhixiang Hu,Jing Li,Dandan Chu,Jiwei Zhang,Zhe Li,Bing Chen,Xiao Zhang,Hongyu Pan,Shengli Li,Hechun Lin,Lei Liu,Mingxia Yan,Xianghuo He,Ming Yao +15 more
TL;DR: The identification of a lncRNA signature associated with metastasis of non-small cell lung cancer (NSCLC) and MetaLnc9 as a driver of metastasis and a candidate therapeutic target for treating advanced NSCLC are reported.
Journal ArticleDOI
LncRNA ID2-AS1 suppresses tumor metastasis by activating the HDAC8/ID2 pathway in hepatocellular carcinoma
Yuqiang Zhou,Lin Huan,Yangjun Wu,Chunyang Bao,Bing Chen,Lu Wang,Shenglin Huang,Linhui Liang,Xianghuo He +8 more
TL;DR: It is demonstrated that ID2-AS1 regulated adjacent ID2 transcription by manipulating chromatin modification and that the newly identified ID2 -AS1/ID2 axis suppressed HCC metastasis by regulating EMT processes.