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Chunyang Bao
Researcher at Fudan University
Publications - 17
Citations - 4180
Chunyang Bao is an academic researcher from Fudan University. The author has contributed to research in topics: Chemistry & Circular RNA. The author has an hindex of 10, co-authored 13 publications receiving 3110 citations. Previous affiliations of Chunyang Bao include Broad Institute & Harvard University.
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Journal ArticleDOI
Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis.
Yan Li,Qiupeng Zheng,Chunyang Bao,Shuyi Li,Weijie Guo,Jiang Zhao,Di Chen,Jianren Gu,Xianghuo He,Shenglin Huang +9 more
TL;DR: Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis and a potential target for drug discovery.
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Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs
Qiupeng Zheng,Chunyang Bao,Weijie Guo,Weijie Guo,Shuyi Li,Shuyi Li,Jie Chen,Bing Chen,Yanting Luo,Dongbin Lyu,Yan Li,Guohai Shi,Linhui Liang,Jianren Gu,Xianghuo He,Shenglin Huang +15 more
TL;DR: The results provide evidence that circular RNA produced from precursor mRNA may have a regulatory role in human cells and characterize one abundant circRNA derived from Exon2 of the HIPK3 gene, termed circHIPK3.
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Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer.
Jie Chen,Yan Li,Qiupeng Zheng,Chunyang Bao,Jian He,Bin Chen,Dongbin Lyu,Biqiang Zheng,Yu Xu,Ziwen Long,Ye Zhou,Huiyan Zhu,Yanong Wang,Xianghuo He,Yingqiang Shi,Shenglin Huang +15 more
TL;DR: The findings suggest that circPVT1 is a novel proliferative factor and prognostic marker in GC and may promote cell proliferation by acting as a sponge for members of the miR-125 family.
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miR-192, a prognostic indicator, targets the SLC39A6/SNAIL pathway to reduce tumor metastasis in human hepatocellular carcinoma
Junwei Lian,Ying Jing,Qiongzhu Dong,Lin Huan,Di Chen,Chunyang Bao,Qifeng Wang,Fangyu Zhao,Jinjun Li,Ming Yao,Lunxiu Qin,Linhui Liang,Xianghuo He,Xianghuo He +13 more
TL;DR: It is newly determined that miR-192 targeted the SLC39A6/SNAIL pathway to reduce tumor metastasis in HCC cells and provided insights into the mechanism underlying miRNA regulation of HCC metastasis and a novel therapeutic target for HCC treatment.
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NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α.
Chunyang Bao,Yan Li,Lin Huan,Yuannv Zhang,Fangyu Zhao,Qifeng Wang,Linhui Liang,Jie Ding,Li Liu,Taoyang Chen,Jinjun Li,Ming Yao,Shenglin Huang,Xianghuo He,Xianghuo He +14 more
TL;DR: A pathway in which TNFα–NF-κB signaling switches off negative regulation by suppressing HNF-1α–mediated expression of miR-194 is identified, revealing insight into the mechanisms linking inflammatory pathways, miRNA, and HCC metastasis.